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Updated On: 18-11-2024

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Trimethobenzamide hcl - @ - Anticholinergics- Antiemetics

Drug Name:
Trimethobenzamide hcl - @ - Anticholinergics- Antiemetics

List Of Brands:

TABAMIDE *

Indication Type Description:

Drug Interaction

Indication

Adverse Reaction

Contra-Indications

Dosages/ Overdosage Etc

Patient Information

Pharmacology/ Pharmacokinetics

Pregnancy and lactation

Drug Interaction:

Antiemetics/ Antivertigo agents- include

Phenothiazines- Chlorpromazine Nausea /Vomiting

Triflupromazine Nausea /Vomiting Perphenazine Nausea /Vomiting

Promethazine Nausea /Vomiting Motion Sickness

Prochlorperazine Nausea /Vomiting

Others- Metoclopramide Nausea /Vomiting

Anticholinergics- Antihistamines- Cyclizine Nausea /Vomiting Motion Sickness Meclizine Nausea /Vomiting Motion Sickness Vertigo Buclizine Motion Sickness

Diphenhydramine Nausea /Vomiting Motion Sickness Vertigo

Dimenhydrinate Nausea /Vomiting Motion Sickness Verigo

Others- Trimethobenzamide Nausea /Vomiting Scopolamine Motion sickness Miscellaneous- Diphenidol Nausea /Vomiting Vertigo Benzquinamide Nausea /Vomiting Phosphated carbhhydrated solution- Nausea /Vomiting

Hydroxyine Nausea /Vomiting Corticosteroids Nausea /Vomiting

Cannabinoids Nausea /Vomiting

Refer Chlorpromazine

Indication:

Control of nausea and vomiting

Adverse Reaction:

Hypersensitivity reactions; parkinson-like symptoms Hypotension or pain following IM injection, Blood dyscrasias, blurred vision Coma, convulsions, depression, Diarrhea, disorientation, Dizziness, drowsiness, Headache, jaundice, Muscle cramps, Allergic skin reactiions.

Contra-Indications:

Hypersensity to the drug

Special precautions: Encephaliteds, gastroenteritis, dehydration, electrolyte imbalance.

Dosages/ Overdosage Etc:

Indications: Control of nausea and vomiting

Dosage: Oral- Adults- 250mg 3 or 4 times a day Children- (30 to 90lb; 13.6 to 40.9kg) -100 to 200mg 3 or 4 times daily.

Patient Information:

Trimethobenzamide may produce drowsiness .

Do not operate motor vehicles or dangerous machinery until their individual

responses have been determined

Ref - USP PDI Vol II 17th Edition (1997)

TRIMETHOBENZAMIDE - SYSTEMIC

1.Allergies-

Tell your doctor if you have ever had any unusual or allergic reaction to

trimethobenzamide, or if you are allergic to benzocaine. Also tell your

healthcare care professional if you are allergic to any other

substances such as foods. preservatives or dyes.

2.Pregnancy-

Studies have not been done in pregnant women. However, although studies

in animals have not shown that trimethobenzamide causes birth defects

it has been shown to increase the chance of miscarriage

3. Breast-feeding-

It is not known whether trimethobenzamide passes into breast milk.

Mothers who are taking this medicine and who wish to breast feed should

discuss this with their doctor.

4.Children-

This medicine should not be used to treat nausea and vomiting in children

unless otherwise directed by your doctor. Some side effects may be more

in children.

5.Older adults-

There is no specific information comparing use of trimethobenzamide

in the elderly with use in other age groups.

6. Other medicines-

When you are using trimethobenzamide it is especially important that

doctor know if you are using any of the following-

CNS depressants- or

Tricyclic antidepressants- taking these medicines with trimethobenzamide

may cause increased CNS depressant or other serious effects.

7. Other medical problems-

The presence of other medical problems may affect the use of

trimethobenzamide. Make sure you tell your doctor if you have any other

medical problems especially-

High fever or

Intestinal infection- using trimethobenzamide may result in serious side

effects.

Pharmacology/ Pharmacokinetics:

Pharmacology:

Mechanism is obscure, but may be medicated through chemoreceptor trigger zone; direct impulsesof vomiting centre are not inhibited

Pregnancy and lactation:

Pregnancy:

Safety for use not established. Use with caution

Lactation:

Safety for use in nursing mother has not been established.

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Disclaimer: Every effort has been made to ensure that the information provided in this Database is authentic and accurate. Commissions or omissions in the database, if any, are purely inadvertent and the site owner shall not accept any liability whatsoever for any adverse consequences of any nature arising to any individual or third party, as a result of usage of this information.