DERIPHYLLIN
Brand:
DERIPHYLLIN
Manufacturer:
ZYDUS
Manufacturer Details
ZYDUS
Compositions:
Etophylline 169.4mg+ heophylline 50.6mg per 2ml injection,
Etophylline 77mg+ Theophylline 23mg TABLETS,
Etophylline 46.5mg+ Theophylline 14mg per 5ml SYRUP,
Etophylline 115mg+ Theophylline 35mg s.r RETATD 150,
Etophylline 231mg+ Theophylline 69mg s.r RETARD 300,
Etophylline 231mg+ Theophylline 69mg s.r OD 300,
Etophylline 346mg+ Theophylline 104mg s.r OD 450,
Etophylline 462mg+ Theophylline 138mg s.r OD 600,
|
Strength
|
Rate
|
Packing Style
|
|
169.4mg+ 50.6mg per 2ml
|
5.70
|
2ml injection
|
|
77mg+23mg
|
4.70
|
10s TABLETS
|
|
46.5mg+14mg per 5ml
|
45.00
|
200ml SYRUP
|
|
115mg+ 35mg s.r.
|
6.30
|
10s RETARD 150
|
|
231mg+69mg s.rl
|
32.20
|
10s RETARD 300
|
|
231mg+ 69mg s.r
|
81.40
|
10s OD 300
|
|
346mg+ 104mg s.r
|
107.90
|
10s OD 450
|
|
462mg +138mg s.r
|
63.10
|
10s OD 600
|
List of Related Indications:
- Asthma cardiac
- Bronchospasm in bronch asthma
- Cardiac insufficiency
- Central respiratory disorders
- Renal cardiac oedema
List Of Drugs:
Indication Type Description:
Drug Interaction:
Potentiated by quinlolones, macrolides, cimetidine, allopurinol, alcohol, estrogen oral contraceptives
Tacrine, inteferon alpha, disulphiram, fluvoxamine, verapramil, mexiletine,
Nizatidine, propranolol, methotrexate, pentoxyfiyline, ticlopodine, propafenone, thibendazole
Avoid betablockers, Diltiazem, fluconazole, ketoconazole, influenza vaccine,
Antagonised bty phenytoin, rifampicin, barbiturates, carbamazepine, primidone, rotonavir,
Sucralfate, isoproterenol, sulphinpyrazole,
Antagonize lithium, benzodiazepines, pancuronium, adenosine,
Seizures with ketamine.
Toxicity with sympathomimetics, St Johns wort, beta-agonists, diuretics, doxapram, corticosteroids,
Smokers have increased metabolism,
Indication:
Bronchial asthma, pulmonary disease with spastic bronchial component
Adverse Reaction:
Nausea, vomiting, epigastric pain, hematemesis,
diarrhea, head ache, insominia,
convulsions, palpitations, flushing,
CNS stimulation, diuresis, hypotension,
extrasystoles, life threatening arrhythmias,
tachypnoea,albuminuria, hyperglycaemia
Contra-Indications:
Active peptic ulcer
Arrhythmias
Porohyria
Seizure disorders
Not for primary treatment of acute attacks
Concomittant use of ephidrine in children
Special precaution-
Cirrhosis,
CCF, pulmonary odema, Cardiac or liver disease. elderly
Fever, sepsis, shock.
Monitor serum levels, do not try to maintain non-tolerated dose.
Cor pulmonale.
Hyperthyroidism. Rapid metaboilizers.
Hypertension. Acute febril illness.
Chronic alcoholism.
Pregnancy
Lactation - not recommended
Dosages/ Overdosage Etc:
Bronchial asthma, pulmonary disease with spastic bronchial component
Injection-
2-4 ml upto 2-3 times daily i.v. ( 2ml in 1 min ) i.m. & s.c.
Also as a combined inj with dextrose
Tablets
1-3 tabs thrice daily after food.
Syrup-
5-10ml 3 times daily
Retard tabs
150mg - 1 tab 2-3 times daily
300mg - 300mg 12 hourly. increase or reduce by 150mg increments if reqd.
Interaction with Food:
To be taken after food
Pregnancy and lactation:
Contradicated for use during pregnancy
Lactation- not recommended
