25mg/50mg/75mg Film coated tablets,
|25mg f.c.||45.00||10s Film coated tablets|
|50mg||67.00||10s Film coated tablets|
|75mg||95.00||10s Film coated tablets|
List of Related Indications:
List Of Drugs:
- Dosulepin - Anti-depressants- (FDC- List ) (Apr 2010)
Indication Type Description:
Dosages/ Overdosage Etc
Pregnancy and lactation
Drug interactions- summary
Barbiturates reduce antidepressant effect of dosulepin
Raised erun concentration with with methylphenidate .
Cigarette smoking enhances metabolism.
Increased risk of ventricular arrhthymias when used with drugs that prolong QT intervals
Should not be given concurrently or within 14 days of stopping MAOIs .
Potentiates catecholamine, sympathomimetics , narcotics, and alcohol
Reduce hypotensive activity of bethanidine , guanethidine
Cholestic jaundice, sexual dysfunction, exacerbation of psychotic manifestation,
cardiac arrhthymias, hypotension, dry mouth, constipation, disturbance of accomodation,
tachycardia, postural hypotension, drowsiness, tremors, and skin rash
Withdrawal symptoms with abrupt cessation, insomnia irrirability, and excessive sweating
Bone marrow depresson, cardiac arrhythmias, and agranulocytosis.
Reports of ventricular fibrilation and renal failure
Hypersensitivity, recent MI , neonate heart block, cardiac arrhythmias, mania,
alcohol, other CNS depressants,
Severe liver disease, prostate disease, children
Epilepsy, hypotension, glaucoma, urinary retension, gradual withdrawal,
Pregnancy, Lactation, elderly
Dosages/ Overdosage Etc:
Date of Approval 2010
For the treatment of neuropathic pain
Adult- initially 25mg tid, gradually increased to 50mg tid if necessary,
alternately as a single dose at night.
Upto 225mg/day may be used in severe depressin.
Elderly- initially 50- 75mg daily
Pregnancy and lactation:
Contraindicated for use during pregnancy