Antimicrobial or immunosuppressive agents may interfer with the development of the immune response. Use only under medical supervision

Active immunisation

Lymphodenoptahy, osteomyelitis, lupoid reactions, disseminated BCG infection and death ( very rare), occur in chilldren with impaired immune response.

Persons with impaired immune response

Special precautions-

Aseptic technique- Tice BCG contains live bacteria, use with aseptic technique. handle and dispose of all equipment supplies, and receptacles in contact with BCG vaccine as bio-hazardous.

Allergic reactions- assess the possiblity of allergic raections Lymphodenopathy- occasionally lymphadenopathy of the regional lymph node which spontaneously resolves itself is seen in young children.

Warnings-                                                                                                                              Do not inject IV ,Sc or intradermally. Use percutaneous administration with multiple puncture disc.

Immune deficiency syndrome- do not use in infants, children or adults with severe immune deficiency syndrome.

Pregnancy- give to a pregnant woman only of clearly needed.

Lactation- decide whether to discontinue the drug or discontinue nursing taking into account the importance of the drug to the mother.

Children- take precautions with respect to infants vaccinated with BCG and exposed to persons with active tuberculosis.

Active immunisation

1. Keep the vaccination site clean until the local reaction has disappeared.

Pregnancy-

Give to a pregnant woman only of clearly needed.

Lactation-

Decide whether to discontinue the drug or discontinue nursing taking into account the importance of the drug to the mother.

Children-

Take preacutions with respect to infants vaccinated with BCG and exposed to persons with active tuberculosis.