Loop diuretics include- Furosemide, Bumetamide, Ethacrynic acid, Torasemide Refer Furosemide

Diuretic

Torsemide

 CNS- headache, dizziness, asthenia, insomnia, nervousness, syncope GI- diarrhea, constipation, nausea, dyspepsia, edema, GI hemorrhage, rectal bleeding

Cardiovascular- ECG abnormality, sore throat, chest pain, artial fibrillation, hypotension, ventricular tachycardia, shunt thrombosis

Respiratory- rhinitis, cough increase

Musculoskeletal- arthalgia, myalgia

Lab test abnormalities- hyperglycemia, hyperuricemia, hypokalemia,hypovolumia

Miscellaneous- excessive urination.

Refer Furosemide

Dosage:

Torsemide may be given any time in relation to a meal.

CHF: Initial dose is 10 to 20mg once daily oral or IV. If the diuretic response is inadequate, titrate the dose upward by approximately doubling until the desired response is acheived.

Chronic renal failure- Initial dose is 20mg once daily oral or IV. If the diuretic response is inadequate, titrate the dose upward by approximately doubling until the desired response is acheived.

Loop diuretics

1. May cause GI upset, take with food or milk

2. Drug will increase urination, take early in the day

3. Notify physician if muscle weakness , cramps, nausea, or dizziness occur

4. Orthostatic hypotension may occur, get up slowly

5. Diabetes mellitus patients- may increase blood glucose levels, affecting urine glucose tests.

6. Photosentivity may occur in some patients. Cution patients to take protective measures (ie Sunscreens, protective clothing) against exposure to ultraviolet light or sunlight

7. Hypersensitivity patients should avoid medications that may increase blood pressure, including OTC products for appetite suppression and cold symptoms

Refer Furosemide