Indication:
LIST OF DRUGS DURING 2007
Sr.No- 48
Name of the Drug- Propofol 10mg +
Lignocaine 1mg per ml injection
Pharmacological Classification- For induction of anesthesia
Date of Approval- 04-04-07
Approved by U.S.FDA on 30-12-2007 (Ref- FDA approved List- 2007)
Induction or maintenance of anesthesia
New Drugs Approved by (DCI) Drug Controller GENERAL - India For Marketing
(Ref- IDMA Publication)
Name of Drug Indication Date of Approval
Propofol Inj Anaesthetic agent 05-05-1998
FIXED DOSE COMBINATIONS APPROVED BY DCG(I)
FROM JANUARY 1961 TILL NOVEMBER 2014
Name of Drug Indication Date of Approval
1.Propofol 1omg + 27-10-2009
Lignocaine 2.5mg per ml injection
Addl.Stgth
For induction of anesthesia
2. Propofol 10mg + 04-04-2007
lignocaine 1mg per ml injection
For induction of anesthesia
Adverse Reaction:
Amorous behaviour, hypotonia, neuropathy, opishotonus. Asthenia, myocardial ischemia. Awareness, extremities pain, fever, increased drug effect, neck rigidity/stiffness, chest/trunk pain
Contra-Indications:
When general anesthesia or sedation are contraindicated; hypersensitivity to propofol or components of the product.
Special precaution:
Special risk patients- use a lower induction dose.Epilepsy, occurance of transcient local pain. Hyperlipidermia.
Pharmacology/ Pharmacokinetics:
Pharmacology: Propofol is an IV sedative agent for induction and maintenance of anesthesia or sedation.
Pharmacokinetics: Profofol is chiefly eliminated by hepatic conjugation into inactive metabolite which are excreted by the kidney.
Pregnancy and lactation:
Pregnancy: Use during pregnancy only when needed
Lactation: Not recommended for use in nursing mothers.
Manufacturer Details