DACOTIN INJ
Manufacturer Details
DR.REDDYS
Compositions:
Oxaliplatin 50mg/100mg vials injection,
|
Strength
|
Rate
|
Packing Style
|
|
50mg/vial
|
2670.00
|
1 injection
|
|
100mg/vial
|
4787.90
|
1 injection
|
List of Related Indications:
- Metastc testiclr & ovarn tumer
List Of Drugs:
- Oxaliplatin- Anti-cancer Drugs -Platinum Coordination Complex-(Oct 1998)
Indication Type Description:
Drug Interaction:
Not reported
Indication:
Metastatic colorectal cancer
Approved by (DCI) Drug Controller GENERAL - India For Marketing
(Ref- IDMA Publication)
Name of Drug Indication Date of Approval
Oxaliplatin Inj Anticancer agent 26-10-1998
Adverse Reaction:
Peripheral sensory neutropathy Pharyngo-laryngeal dyasthesia anemia including imuno-haemolytic anemia
Neutropenia ,thrombocytopenia Nausea, diarrhea Muscositis/stomatitis Alopecia
Raised liver enzymes Allergic reactions Fever Ototoxicity Rash Arthalgia Back pain, colitis
Renal function disturbances tempororary loss of visual acuity
intestinal lung disease ( sometimes fatal )
Contra-Indications:
Severe renal impairment Neutropaenia Thrombocytoma Peripheal sensory neuropathy Myelosuppression Pregnancy Lactation
Special precautions
Moderate renal impairment Monitor renal function
History of sensitivity to platinum compds Monitor for allergic reactions
Discontinue immediately if anaphyloid reactions occur and do not rechallenge
Perfrom neurological eaxm, before each dose
Discontinue or reduce dose if parathesia or dysaethesia are present
Peform full blood count and white cell differntial before each dose
Discontinue if unexplained respiratory symptoms occur
Dosages/ Overdosage Etc:
Indication-
Metastatic colorectal cancer
Dosage-
85mg/m2 every two weeks by iv infusion over 2-6 hrs prior to admin of 5FTU
Pregnancy and lactation:
Use contraindicated. Observe caution
