Potentially hazardous interactions- Increased levels of theophyline and cyclosporin,warfarin. Effects potentiated,disulfram-like reactions with alcohol.

Antacids reduce absorption of norfloxacin from gut.

Probenacid reduces urinary excretion of norfloxacin.

Respiratory tract infections Surgical infections Gynaecological infections Intra-abdominal infections

Rarely hypersensitivity reactions, Facial and laryngeal oedema, Hypotension, bronchospasm. Nausea,vomiting, heartburn, Metallic taste,

Headache, dizziness, Depression,insomnia, Rash,dry mouth, Fever,arthralgia. Rarely eosinophilia,bone marrow depression.

Hypersensitivity,neurological disorders,including convulsion, Blood dyscrasias Pregnancy,lactation,children.

Special precautions-

Moderate renal impairment, History of susceptibility to seizures,alcohol intake. Ensure adequate hydration and urine output.

Respiratory tract infections Surgical infections Gynaecological infections Intra-abdominal infections

Dosage-

Usually 1 tab bid for 5-10 days depending on severity of response

Use contraindicated. Observe caution