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Updated On: 18-11-2024

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Guaiphenesin -@ -Expectorant-(Aug 2008)

Drug Name:
Guaiphenesin -@ -Expectorant-(Aug 2008)

List Of Brands:

VENTORLIN EXPECTORANT
BRONCHOSOLVIN
BRICAREX EXPECTORANT
GRILINCTUS

Indication Type Description:

Drug Interaction

Indication

Adverse Reaction

Contra-Indications

Dosages/ Overdosage Etc

Patient Information

Pharmacology/ Pharmacokinetics

Interaction with Food

Drug Interaction:

None reported.

Drug/Lab test interaction: May cause a colour interference with certain laboratory determinatins of 5-hydroxindoleactic acid (5-HIAA) and vanillyl mandelic acid(VMA)

Indication:

U.S FDA APPROVED DRUGS FROM 01-01-08 TO 31-12-08

Drug name Indication Date of Approval

188. Guiaphenesin ER Tablet (600mg) 26-08-08

For the treatment of productive cough

accompanied by phlegm

Symptomatic relief of non-productive cough

New drugs approved For Marketing by Drug Controller General of India(DCGI )

during the period January 1988 to November 2014

(Ref- IDMA Annual Publication 2015)

Name of Drug Indication Date of Approval

1.Guaiphenasin syrup 133mg/5ml 18-12-2009

For the treatment of productive cough accompanied by phlegm

2. Guiaphenesin ER tablet 600mg 28-08-2008

For the treatment of productive cough accompanied by phlegm

3. Guiaphenesin ER tablets 1200mg 16-05-2009

For the treatment of productive cough accompanied by phlegm

Adverse Reaction:

GI discomfort, nausea and vomiting, hyperuricaemia.

Contra-Indications:

Hypersensitivity go guaiphenesin

Warnings-

Not for persistent cough as occurs with smoking , asthma or emphysema or where cough is accompanied by excessive secretions

Special precautions:

Persist cough may indicate serious conditions. If cough persiste more than 1 week , tend to recur or accompanied bynhigh fever, rash or persistent headache, consult physician. Excessive dosage may cause nausea and vomiting

Dosages/ Overdosage Etc:

Indication-

Symptomatic relief of non-productive cough

Dosage

Adults and children > 12 yrs- 100- 400mg every 4 hrs.

Do not exceed 2.4g /day

Children 6-12 yrs - 100-200mg every 4 hours . Do not exceed 1.2g/day

Children 2-6 yrs - 50 -100mg every 4hours . do nott exceed 600mg/day

Patient Information:

Ref - USP PDI Vol II 17th Edition (1997)

1.Allergies-

Tell your doctor if you have ever had any unusual or allergic reaction to

Guaifenesin. Also tell your healthcare care professional if you are allergic

to any other substances such as foods. preservatives or dyes.

2.Pregnancy-

Studies have been done in several groups of women taking guaiphenesin

during pregnancy. Birth defects can occur in women taking guaiphensin during

pregnancy. You must discuss this with your doctor.

3. Breast-feeding-

Guiaphesin has not been reported to cause problems in nursing mothers.

4.Children-

Guaiphenesin should not be given to children younger than 2 years of age

unless you have discussed this with your doctor.

5.Older adults-

This medicine is not expected to cause different side effects or problems in

older people than in younger adults.

Pharmacology/ Pharmacokinetics:

Pharmacology:

Guaiaphenesin is claimed to enhance the output of respiratory tract fluid by reducing adheiveness and surface tension facilitating the removal of viscous muscus, as a result nonproductive coughs become more productive and less frequent.

Interaction with Food:

Reports not available

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