Drug Information

Drug Interaction:

Antiemetics/ Antivertigo agents- include Phenothiazines- Chlorpromazine Nausea /Vomiting Triflupromazine Nausea /Vomiting Perphenazine Nausea /Vomiting Promethazine Nausea /Vomiting Motion Sickness Prochlorperazine Nausea /Vomiting Others- Metoclopramide Nausea /Vomiting Anticholinergics- Antihistamines- Cyclizine Nausea /Vomiting Motion Sickness Meclizine Nausea /Vomiting Motion Sickness Vertigo Buclizine Motion Sickness Diphenhydramine Nausea /Vomiting Motion Sickness Vertigo Dimenhydrinate Nausea /Vomiting Motion Sickness Verigo Others- Trimethobenzamide Nausea /Vomiting Scopolamine Motion sickness Miscellaneous- Diphenidol Nausea /Vomiting Vertigo Benzquinamide Nausea /Vomiting Phosphated carbh } Nausea /Vomiting hydrated solution } Hydroxyine Nausea /Vomiting Corticosteroids Nausea /Vomiting Cannabinoids Nausea /Vomiting Refer Chlorpromazine

Indication:

New drugs approved For Marketing by Drug Controller General of India(DCGI )

during the period January 1988 to November 2014

(Ref- IDMA Annual Publication 2015)

Name of Drug Indication Date of Approval

Hydroxyzine hydrochloride 20-08-2010

SR Tablets 25/50/75mg

For the management of pruritus due to allergic conditions such as

chronic urticaria, and atopic contact dermatoses and in histamine-

mediated pruritus

Adverse Reaction:

CNS depression,paradoxical CNS stimulation(chidren), dry mouth, thickened respiratory secretions, constipation, urinary retension, blurring of vision, bradycardia,followed by tachycardia and arrythmias, GI disturbances,blood dyscrasias, headache, giddiness, hypotension, tinnitus and confusion.

Contra-Indications:

Pregnancy,lactation,neonates,obstruction of GIT,urinary outflow,paralytic ileus.

Special precautions:

Renal impairment,nmay impair judgement and dexterity.

Lactation,CVS disease, glaucoma, epilepsy, peptic ulcer,BHP.

Dosages/ Overdosage Etc:

Date of Approval 2010

Indications:

Symptomatic relief of anxiet and tension.

Dosage:

Oral Adults- 50 to 100mg 4 times a day.

Children(Below 6 years)- 50mg in divided doses. Children(above 6 years ) 50 to 100mg/day in divided doses.

Patient Information:

Antiemetics/ Antivertigo agents- include Phenothiazines- Chlorpromazine Nausea /Vomiting Triflupromazine Nausea /Vomiting Perphenazine Nausea /Vomiting Promethazine Nausea /Vomiting Motion Sickness Prochlorperazine Nausea /Vomiting Others- Metoclopramide Nausea /Vomiting Anticholinergics- Antihistamines- Cyclizine Nausea /Vomiting Motion Sickness Meclizine Nausea /Vomiting Motion Sickness Vertigo Buclizine Motion Sickness Diphenhydramine Nausea /Vomiting Motion Sickness Vertigo Dimenhydrinate Nausea /Vomiting Motion Sickness Verigo Others- Trimethobenzamide Nausea /Vomiting Scopolamine Motion sickness Miscellaneous- Diphenidol Nausea /Vomiting Vertigo Benzquinamide Nausea /Vomiting Phosphated carbh } Nausea /Vomiting hydrated solution } Hydroxyine Nausea /Vomiting Corticosteroids Nausea /Vomiting Cannabinoids Nausea /Vomiting Refer Chlorpromazine

1.May produce drowsiness,patients should observe caution while driving or performing other tasks requiring alertness.

2.Avoid alcohol or other CNS depressants, that may intensify this effect..

Interaction with Food:

Not known.

Pregnancy and lactation:

Use contraindicated Observe caution

Hydroxyzine@( ** )- Antianxiety agent- (Aug 2010)

Drug Interaction

Indication

Adverse Reaction

Contra-Indications

Dosages/ Overdosage Etc

Patient Information

Interaction with Food

Pregnancy and lactation