Drug Interaction:
Antihistamines Include: First Generation ( Non-selective )- Ethanolamine- Carbinoxamine. Clemastine, Diphenhydramine. Ethylenediamines- Pyrilamine, Triplennamine Akylamines- Brompheneramine, Chlorpheniramine, Dexchlor pheniramine,Pheniramine,Triprolidine
Phenothiazines- Methidilazine, Promethizine, trimeprazine Piperidines- Azatadine, Cyproheptadine, Phenindamine Miscellaneous- Astemazole, Loratadine, Terfenadine Second Generation ( Peripherally selective ) Phthalazinone - Azelastine Piperazine - Cetrizine Refer - Chlorpheniramine maleate
Indication:
Common cold Allergic conditions ================================================================================== Antihistamines Include: First Generation ( Non-selective ) ---------------------------------------------- Ethanolamine- Carbinoxamine. Clemastine, Diphenhydramine. Ethylenediamines- Pyrilamine, Triplennamine Akylamines- Brompheneramine, Chlorpheniramine, Dexchlor pheniramine,Pheniramine,Triprolidine ---------------------------------------------------------------------------------------------------------------------------------------- Phenothiazines- Methidilazine, Promethizine, trimeprazine Piperidines- Azatadine, Cyproheptadine, Phenindamine Miscellaneous- Astemazole, Loratadine, Terfenadine Second Generation ( Peripherally selective ) Phthalazinone - Azelastine Piperazine - Cetrizine Refer - Chlorpheniramine maleate =======================================================================================
Adverse Reaction:
CNS depression,paradoxical excitation in children, Dryness of mouth, blurring of vision, Retention of urine, constipation, Bradycardia followed by tachycardia and arrhythmias. GI upsets, Blood dyscrasias, Headache, nausea, Giddiness, Hypotension, Parathesias and tinnitus.
Contra-Indications:
Hypersens,newborn,children,lactation. GIT/urinary outflow obstruction, paralytic ileus. Special precautions: Elderly, driving, CVS disorders, hypertension, epilepsy, BHP, pregnancy.
Dosages/ Overdosage Etc:
Common cold Allergic conditions 25mg 2-3 times a day or 50mg twice daily
Patient Information:
Refer - Chlorpheniramine maleate
Pharmacology/ Pharmacokinetics:
Antihistamines Include: First Generation ( Non-selective ) ---------------------------------------------- Ethanolamine- Carbinoxamine. Clemastine, Diphenhydramine. Ethylenediamines- Pyrilamine, Triplennamine Akylamines- Brompheneramine, Chlorpheniramine, Dexchlor pheniramine,Pheniramine,Triprolidine ---------------------------------------------------------------------------------------------------------------------------------------- Phenothiazines- Methidilazine, Promethizine, trimeprazine Piperidines- Azatadine, Cyproheptadine, Phenindamine Miscellaneous- Astemazole, Loratadine, Terfenadine Second Generation ( Peripherally selective ) Phthalazinone - Azelastine Piperazine - Cetrizine Refer - Chlorpheniramine maleate =======================================================================================
Interaction with Food:
None reported
Pregnancy and lactation:
Antihistamines Include: First Generation ( Non-selective ) ---------------------------------------------- Ethanolamine- Carbinoxamine. Clemastine, Diphenhydramine. Ethylenediamines- Pyrilamine, Triplennamine Akylamines- Brompheneramine, Chlorpheniramine, Dexchlor pheniramine,Pheniramine,Triprolidine ---------------------------------------------------------------------------------------------------------------------------------------- Phenothiazines- Methidilazine, Promethizine, trimeprazine Piperidines- Azatadine, Cyproheptadine, Phenindamine Miscellaneous- Astemazole, Loratadine, Terfenadine Second Generation ( Peripherally selective ) Phthalazinone - Azelastine Piperazine - Cetrizine Refer - Chlorpheniramine maleate =======================================================================================
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