Nondepolarizing Neuromuscular Blockers include- Pipercuranium, Vecuronium,Doxacuranium, Tobocurane, Mivacuranium,Rocuronium, Cisatracurarium, Atracurarium,Pancuronium Refer- Pancuronium 

Expected to interact similarly to other nondepolarizing neuromuscular blockers

Adjunct to general anesthesia 

Nondepolarizing Neuromuscular Blockers include- Pipercuranium, Vecuronium,Doxacuranium, Tobocurane, Mivacuranium,Rocuronium, Cisatracurarium, Atracurarium,Pancuronium Refer- Pancuronium

Arrhythmias, abnormal ECG, tachycardia. Nausea, vomiting. Asthma, bronchospasm, wheezing, hiccup. Rash.

Hypersensitivity to the drug

Special precaution: Tolerance. Malignant hyperthermia. Onset time.

Approved by FDA on March 17, 1994

Adjunct to general anesthesia

Dosage:

For IV use only. Individualise dose

Overdosage-

Symptoms Extended skeletal muscle weakness, decreased respiratory reserve, lower tidal volume, prolonged apnea, cardiovascular collapse and sudden release of histamine. sufficiently excessive . doses of nondepolarizing muscle relaxants have no antidote.

Treatment

1. A peripheral nerve stimulator may be used to assesss the degree of residual neuromuscular blockade

2. For residual neuromuscular blockade with respiratory paralysis or inadequate ventilation, maintain airway and administer manual or mechanical ventilation.

Missed dose-

1. If you miss a dose of this medicine, take it as soon as possible.

2. However, if it is almost time for next dose, skip the missed dose and go back to your regular dosing schedule.

3. Do not double doses.

Pharmacology:

Rocuronium injection is a nondepolarizing neuromuscular blocking agent with a rapid to intermediate onset and intermediate duration