Cisatracurium besylate - Neuromuscular blockr- Adjunt to ane
Drug Name:
Cisatracurium besylate - Neuromuscular blockr- Adjunt to ane
List Of Brands:
Indication Type Description:
Pharmacology/ Pharmacokinetics
Drug Interaction:
Nondepolarizing Neuromuscular Blockers include-
Pipercuranium, Vecuronium,Doxacuranium, Tobocurane, Mivacuranium,Rocuronium, Cisatracurarium, Atracurarium,Pancuronium
Refer- Pancuronium
Anticonvulsant- resistence to neuromuscular blocking action of nondepolarizing agents has been demonstrated Isoflurane or enflurane-
when administered with nitrous oxide/oxygen may prolong clinically effective duration of action
Succinylcholine- time to onset of action is faster following with prior administration of succinylcholine
Indication:
LIST OF NEW DRUG APPROVED FROM 01-01-2016 To TILL DATE
BY NEW DRUG DIVISION - DRUG CONTROLLER GENERAL- INDIA
Sr.No Name of Drug Indication Date of Issue
2. Cisatracurium Besylate Bulk & 14-03-2016
2mg/ml Injection
As an adjunct to general Anesthesia, to facilitate tracheal
intubation and to provide skeletal muscle relaxation
during Surgery
Approved by DCG INDIA (Ref- DCGI approved List- 01-01-2016 To Till Date
Adjunct to general anaesthesia
Nondepolarizing Neuromuscular Blockers include-
Pipercuranium, Vecuronium,Doxacuranium, Tobocurane, Mivacuranium,Rocuronium, Cisatracurarium, Atracurarium,Pancuronium
Refer- Pancuronium
Adverse Reaction:
Bradycardia, hypotension, flushing, bronchospasm, rash.
Contra-Indications:
Hypersensitivity to the drug
Special precaution:
Endotracheal intubation.
Neuromuscular diseases,
Burns.
Dosages/ Overdosage Etc:
Indication-
Adjunct to general anaesthesia
Dosage:
Administer IV only
Overdosage- Symptoms
Extended skeletal muscle weakness, decreased respiratory reserve, lower tidal volume, prolonged apnea, cardiovascular collapse and sudden release of histamine. sufficiently excessive . doses of nondepolarizing muscle relaxants have no antidote.
Treatment
1. A peripheral nerve stimulator may be used to assesss the degree of residual neuromuscular blockade
2. For residual neuromuscular blockade with respiratory paralysis or inadequate ventilation, maintain airway and administer manual or mechanical ventilation.
Missed dose-
1. If you miss a dose of this medicine, take it as soon as possible.
2. However, if it is almost time for next dose, skip the missed dose and go back to your regular dosing schedule.
3. Do not double doses.
Pharmacology/ Pharmacokinetics:
Pharmacology:
Cisatracurium is a nondepolarizing skeletal muscle relaxant
Pregnancy and lactation:
Pregnancy:
Use only when needed.
Lactation:
Excercise caution following administration to a nursing woman
