Reports not available

Ear, nose throat infections

Otitis media Sinusitis

Lower respiratory tract infections

Pneumonia

Urinary tract infection

Nausea, vomiting,

Abdominal pain,

Dyspepsia and headache

Hypersenaitivity to cephalosporins

Special precautions-

Reports not available

Indication-

Ear, nose throat infections

Otitis media Sinusitis

Lower respiratory tract infections

Pneumonia

Urinary tract infection

Dosage-

One tablet two times as [per physician advise.

Refer - cephalosporins

Pharmacology

Cefixime kills bacteria by interfering in the synthesis of thebacterila cell wall. Cefixime binds with high affinity to penicillin-binding proteins in the bacterial cell wall thus interfering with peptogoglycan synthesis.

Peptidoglycan is a heteropolymeric structure that proviodes the cell wall with mechanical stability. Ambroxol reduces the secretin and viscocity of the mucus but the exact mechanism is not clear.

It shows protective effects in the lung tisues may be due to antioxidant activity together with other mechanisms.

Lactobacilius acidophilus breakdowns food to produce lactic acid, hydrogen peroxide,and other by-products that make the enviroment hostile for undesired organisms, thereby prevents growth of pathogenic organisms.

Pharmcokinetics

Cefixine is abosirbed slowly afteroral administrationt. Its absolute bioavailability is asround 50% when compared to intervenous dose. After a 200mg oral dose peak plasma concentration of 2.7mg/l is acheived between 3 and 4 hrs in fasting volunteers . In non-fasting volunteers a slight delay in reaching Cmax is observed.

Refer - cephalosporins