Antimetabolites Radiotherapy Thrombocytopaenic drugs Lithium Bone imaging results

Reduction in duration of neutropenia and incidence of febrile neutropenia dure to chemotherapy

Skeletal joint and muscle pain Inj. site pain Non-cardiac chest pain Headache Splenomegaly Splenic rupture Leucocytosis ARDS Anaphylaxis Angioedema Urticaria Reversible elevated uric acid Alkaline phosphatase and lactate dehydrogenase

Hypersensitivity to E.Coli derived products Secondary acute or chronic myeloid leukemia Myledysplastic syndrome Lactation Special precautions- Use undrer specialised supervision Acute leukemia patients receiving mylesuppresive chemotherapy High-dose chemotherapy Discontinue if signs of adult respiratory distress syndrome Monitor CBC and platelet count before and during thderapy for signs of splenic rupture Sickle cell disease Sepsis Moderate to severe organ impairment Pregnancy

Reduction in duration of neutropenia and incidence of febrile neutropenia dure to Chemotherapy

Dosage-

Single 6mg sc injection for each chemotherapy cycle given approx. 24 hours following chemotherapy Not recommended for patients belw 18 years

Use contraindicated. Observe caution