Iron containing products include- Ferrous Sulphate, Ferrous gluconate,Ferrous fumerate, Polysaccharide -Iron Complex, Iron with Vitamin C Refer - Ferrous Fumarate

 Ferrous Ascorbate- With tetracycline - Mutual interference with absorption , should not be administered concurrently.

With Vitamin E- Haematogical response to iron therapy may be impaired and Vitamin E requirements increased.

Patient Obervation recommended With Carbonate

Antacids- Iron absorption is decreased

Folic Acid- None has been reported

Nausea, Epigastric Pain, Diarrhoea Allergic Skin rash Fever

Paitients receiving blood transfusions and anemia where Iron deficiency is not present

Iron Deficiency Anemia

Pharmacokinetics- Folic acid rapidly absorbed orally and converted to tetrahyrofolate, the metabolically active form. About 70-80% of 2mg oral dose of Folic acid is absorbed. It is readily from the upper gastrointestinal tract. It is well distributed into plasma ( 70% ) and extracellular fluid. Excess Folic acid is excreted largely unchanged in the urine. Rationale for the Combination- Clinical trials have proved the efficacy of ferrous ascorbate as iron supplement. Absorbtion of Ferrous Salt is three times more than Ferric Salt. The difference in absorption rates increases with increasing dose. Hence Ferrous salts are recommended in community- based programs. Ascorbic acid increases the absorption of ferrous salts upto 10 times. Folic acid is the one of the causes of anemia in pregnant women, so addition of this in the combination is beneficial