Not available

Diabetic neuropathic ulcers

Adverse reactions-

Ulcer related adverse reactions - infection, cellulitis, or osteomyletis

Hypersensitivity reactions

Special Reactions -

Do not use it on wounds that close by primary intention

Exposed joints, tendons, ligaments, bone- the effects of becapermin exposed joints , tendons, ligaments, and bones have not been established in humans

Hypersensitivity - if application site reactions occur, consider the possibility of sensitization or irritation caused by parabens or m-cresol.

Pregnancy- give becaplermin to pregnannt woman only if clearly indicated.

Lactation- excercise caution when becaplermin is administered to breast-feeding women.

Children- safety and efficacy of becaplermin in children and adolesents younger than 16 years of age have not been established.

Elderly- no overall differences in safety or effectiveness were observed between patients
younger than 65 years and patients 65 years of age

Indication-

Diabetic neuropathic ulcers

Dosage -

For external use only.
Apply calculated length of gel by sqeezing on a clean mesuring
surface eg. wax paper. The measured becaplermin is then transferred from the clean
measuring surface using an application aid and then spread over the entire area to
yield a thin continuous layer of approx. 1/16 of an inch thickness

1. Advice patients to wash their hands before applying becaplermin

2. Use a cotton swab , tongue depressor, or other application aid to apply becaplermin

3. Only apply becaplermin once  a day in a carefully measured quantity.
   Evenly spread the measured quantity of gel over the ulcerated area to yeild
   a thin conitinous layer of approx,  1/16th of an inch thickness

Pregnancy-
Give becaplermin to pregnannt woman only if clearly indicated.

Lactation-
Excercise caution when becaplermin is administered to breast-feeding women.

Children-
Safety and efficacy of becaplermin in children and adolesents younger than 16 years
of age have not been established.

Elderly-
No overall differences in safety or effectiveness were observed between patients
younger than 65 years and patients 65 years of age