Sinecatechins - @ -Topical Wound Healing Agents
Drug Name:
Sinecatechins - @ -Topical Wound Healing Agents
List Of Brands:
Indication Type Description:
Pharmacology/ Pharmacokinetics
Drug Interaction:
Not known
Indication:
External genital and perianal warts
Adverse Reaction:
Adverse reactions leading to discontinuation or dose interrruption was 5%
Local site reactions- erythema, local pain, skin erosion, ulceration, vesicles, dysuria
genital herpes
Dermatological - bleedding 2%, burning 60%, discharge 3%, erosion/ulceration 45%
eryhthema 65%, pruritus 55%, rash vasicular 20%
Miscellaneous- edema 40%, induration 30%, pain/discomfort 50%
Contra-Indications:
Warning/precautions-
Open wounds- avoid using sinecatechins on open wounds
Immunosuppressed patients- safety and efficacy in immunosuppressed patients have not been established
Photosentivity- advice patients to avoid exposure of the genital and perianal area to sunlight or ultraviolight
Pregnancy- no adequate and well documented studies in pregnant women. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Lactation- not known if topically applied sinecatachins are excreted in breast milk.
Children- Safety and efficacy in children have not been established
Dosages/ Overdosage Etc:
Indications-
External genital and perianal warts
Dosage-
Apply 3 times per day to all external genital and perianal warts. About 0.5 cms
strand of the ointment should be applied to each wart using the finger, dabbing it to ensure complete coverage and leaving a thin layer of the ointment on the warts
Patient Information:
1. For external use only.
2. Avoid using sinecatechins on open wounds
3. Avoid exposure of the genital and parianal warts to sun light or UV light
Pharmacology/ Pharmacokinetics:
Pharmacology-
The mode of action of sinecatechine ointment invloved in the clearance of genital and perianal warts is unknown
Pregnancy and lactation:
Pregnancy-
No adequate and well documented studies in pregnant women. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Lactation-
Not known if topically applied sinecatachins are excreted in breast milk.