Reduced cellular hypersensitivity

Systemic -  sneezing, coughing, itching, shortness of  breath, abdominal cramps, vomiting,
diarrhea, tachycardia, hypotension, respiratory failure,

Progession of delayed  reaction-  necrosis, and ulceration is possible

Local -redness, swelling, bruising, pruritus, excoriation, discoloration of the skin,
vesiculation, bullae dermal exfoliation, cellulitis

History of previous unacceptable adverse reactions.

Special Precautions/Warnings-

Type 1 allergy - product should not be used to diagnose or treat Type 1 allergy to C.albicans

Immunodeficiency - it may be advisable to skin test patients at high risk of tuberculosis with antigens in addition to tuberculin to confirm patients state of cellular immunity

Local reactions- severe local reactions may require additional measures as appropiate

Systemic reactions - usually occur within 30 minutes after the injection of antigen

Route of administration- do not inject into the blood vessel. It must be not given IV.

Hypersensitivity - facilties, medications necessary to treat all potential local and systemic
reactions must be avialable

Pregnancy- problems in pregnancy are unlikely. Give to pregnant women only if required

Lactation- Problems in breast feeding are unlikely

Children- safety and efficcy has not been established

Elderly - DTH response to C albicans may be diminished in elderly patients, since the aging process is known to alter cell-mediated immunity.

Indications-

Reduced cellular hypersensitivity

Dosage-
skin test antigen is administered intradermally  on the volar surface of the forearm or
 on the outer aspect of the upper arm. The test dose is 0.1ml. Cleanse the skin with
70% alcohol before applying the skin test.

Pregnancy-
Problems in pregnancy are unlikely. Give to pregnant women only if required

Lactation-
Problems in breast feeding are unlikely

Children-                                                                                                                              Safety and efficacy has not been established

Elderly -
DTH response to C albicans may be diminished in elderly patients, since the aging
process is known to alter cell-mediated immunity.