No systemic adverse reaction reported.

Occassional hypersnsitivity  - localized dermatitis may occur,  in which case discontinue
medication

Hypersensitivity to hydroquinone

Special Precautions/Warnings-

Bleaching- hydroquinone is a skin bleaching agent which may produce  unwanted cosmetic effects if not used as directed
 
Irritation-  to evalutate possibility to irritation or sensitivity each patient should start by applying the medication to a small portion of unbroken  skin at or near the pigmented area over a period of several days. If no irritation occurs within 24 hours, begin treatment .
Minor redness is not necessarily a contraindication.

Sun exposure- during the depigmentation maintenance treatment, subsequent to intensive
depigmentation therapy sun exposure of the bleached skin should be avoided to prevent
repigmentation.

For external use only- avoid contact with eyes. In case of accidental contact, patient should rinse eyes throughly with water and contact physician. A bitter taste and antiseptic effect may occur if applied to the lips.

Sensitivity- A mild transient stinging may occur in people with sensitive skin. Do not use on
broken or irritated skin.

Peroxide- concurrent use of peroxide may result in transient  dark staining of the skin due to oxidation by hydroquinone . Staining can be removed by discontinuing concurrent use and by normal soap cleaning.

Pregnancy- Should be used only if required.Consult a physician if you are pregnant or intend to become pregnant within 3 months.Follow your doctors advice.

Lactation-  caution is adviced when topical hydroquinone is used by a nursing mother.

Children- Data not established. Not recommended for children below 12 years of age

Indication-

Hyperpigmented skin

Dosage-

Apply to affected areas twice daily. discontinue if lightening effect does not occur after 2 months

Children - Not recommended
 

1. For external use only. Avoid contact with skin

2. Do not use on irrited denuded or damaged skin.

3. Discontinue use and consult physician if rash or irritation develops

Pregnancy-
 Should be used only if required.Consult a physician if you are pregnant or intend to
become pregnant within 3 months.Follow your doctors advice.

Lactation- 
Caution is adviced whentopical hydroquinone is used by a nursing mother.

Children-
Data not established. Not recommended for children below 12 years of age