MAOIs beta-blockers, alcohol, diuretics, fibrates, corticosteroids, oral contraceptives

Nifedipine, ACE inhibitors, angiotensin II antagonists, octreotide, other hypoglycemics

Salicylates, sulphanamides, quinine , quinidine, growth thyroid hormones, danazol,

Diazoxide, clonidine, lithium, asparaginase, nicotinic acid, anabolic steroids,
oxymethaolone, isonazid, phenothiazines

Diabetes

Hypoglycaemia, hypokalaemia , odema,

Injection site reactions ( inculding lipodistrophy )

Visual disturbances

Sports events- Restricted /banned

Special precautions/Warnings-

Severe hypoalbuminemia,

Patients transferred to human insulin should be adviced that the early warning symtoms
of hypoglycemia may be less pronounced than with insulins from an animal source

Change in strength, brand, type, origin  and or method of manufacture may require
change in dosage.

Dose changes may be required with infectin, stress, excercise , trauma, surgery,
and at puberty

Renal or hepatic impairment,

Elderly, Pregnancy, lactation

Indication-

Diabetes

Dosage-

Adult and children over 2 years by s.c. inj once or twice daily in combination with
meal related short or rapid acting insulin

Dosage according to individual requirements
In combination with oral antidiabetic agents, Initially 10 iu or 0.1 -0.2iu/kg once daily

Titrate dose according to individual requirements

Excercise  caution while using pregnancy and lactation