Special Precautions/Warnings-

Renal function impairment -
The dose requirements for insulin may be reduced in patients with renal impairment

Hepatic function impairment-
The dose requirements for insulin may be reduced in patients with hepatic  impairment

Indication-

Diabetes mellitus

Dosage-

0.5 and 1unit/kg /day. when used with a meal related subcutaneous injection regimen,
50% to 70% of total insulin requirements may be provided by Novolog and the
reminder by an intermediate or long acting insulin.

Because of Novologs comparitively rapid onset and short duration of glucose-lowering
activity, some patients may require more basal insulin and more total insulin to prevent
premeal hyperglycemia when using Novolog  than using human regular insulin