Alcohol or other CNS depressants.

Concomittant ritonavir use not recommended

Caution with other potent CYP3A4  inhibitors (eg, ketoconazole )

Allergic Rhinitis
Seasonal allergic   rhinitis

Dysgeusia,  epistaxis,  headache, somnolence

Special precautions-
Avoid use in recent nasal  ulcers, nasal sugery, or nasal trauma

Respiratory tract tuberculosis, Infections (eg fungal ,bactrial, viral, ocular herpes simplex)

Avoid exposure to chicken poxand measles, if exposed  consider anti-infective prophylactic
therapy

If adrenal insufficiency exists following systemic corticostroid therapy , replacement with
topical corticosteroidsmay exacerbate symptoms of adrenal insufficiency ( eg lassitude,
depression)

Monitor growth routinely in children

Monitor for hypercortiicism and HPA axis suppression ( if occur discontinue gradually ),
and Canida infections or other nasal mucosal changes

History of increased intraocular pressure, glaucoma, and/ot cataract.
Monitor any changes in vision

Avoid eyes.

Pregnancy, Lactation

Indication-
Allergic rhinitis
Seasonal allergic  rhinitis

Dosage-
1 spay per nostril twice daily
Children - not recommended

Observe caution if used during pregnancy or administered to breast feeding woman