Tricyclic antidepressants
MAOIs, CNS depresants, diazoxide, ansthetics, antihypertensives

Essential hypertension

Tachycardia, hypotension, flushing,
Angina, headache, arthralgia, myagia,

SLE like syndrome with doses above 100mg daily
Proteinuria,  increased plasms creatinine, hematuria

Renal failure, urinary retension,
Rarely renal damage, peripheral neuritis, paralytic ileus

Blood dyscrasias

Idiopathic SLE, tachycardia, aortic or mitral stenosis,
Constrictive pericarditis coronary pulmonale, dissecting aortic aneurysm,
Ist half of pregnancy

Special precautions-
Coronary or cerebrovascular disease,
 Severe renal failure, hepatic dysfunction.

Withdraw gradually
Lactation

Indication-
Essential hypertension

Dosage-
12.5mg thrice daily

Use contraindicated during pregnancy and lactation. Observe caution.