Phenylephrine hcl ( ** ) - @ - Vasopressors used in shock- (FDC- List )- (Jan 2008)

Drug Name:
Phenylephrine hcl ( ** ) - @ - Vasopressors used in shock- (FDC- List )- (Jan 2008)

List Of Brands:

Indication Type Description:

Drug Interaction

Indication

Adverse Reaction

Contra-Indications

Dosages/ Overdosage Etc

Patient Information

Pharmacology/ Pharmacokinetics

Pregnancy and lactation

   

Drug Interaction:

VASSOPRESSORS USED IN SHOCK-  includes-
 
Inotropic effects -
Isoproternol, Dobutamine, Dopamine, Ephinephrine, 
 
Mixed  effects- 
Norephinephrine, Ephedrine, Mephentermine
 
Pressors effects-
Metaraminol
Methoxamine
Phenylephrine
 
 
Interacting drugs- summary
                          
+ Phenylephirine
 
Bretylium  
  bretylium may potentiate the action of vasopressors on adrenergic
   receptors, possibly resulting in arrthythmias
 
Guanethidine  
   guanethidine may increase the pressor response of the direct-acting  
   vasopressors, possibly resulting in severe hypertension
 
Halogenated  hydrocarbon anesthetics  
    halogenated hydrocarbon anesthetics may sensitise the effects of 
    catecholamines. Use of vasopressors may lead to serious  
     arrthythmias, use with extreme caution
 
Oxytocic drugs 
     if vasopressor drugsare used in obstertics to correct hyoptension 
     or added to local anesthetic solution, some oxytocic drugs may 
     cause severe persistent hypertension
 
Tricyclic antidep  
    tricyclic antidepressants have both increased and decreased 
     the sensitivity to IV phenylephrine                                                       
 
Monoamine  oxidase inhibitors (MAOIs)
    MAOIs may significantly enhance the adrenergic effects of   
    phenylephrine  and its pressor response may be increased .                                    
     Avoid this combination.