Calcium Channel Blockers include-

• Bepridil, Diltiazem, Felodipine, Isradipine, Nicardipine, Nifedipine, Nimodipine, Verapramil, Amlodipine, Nisodipine, Clevidipine, Lercandipine
• Refer verapramil-

Chronic stable angina

Calcium Channel Blockers include - Bepridil, Diltiazem, Felodipine, Isradipine, Nicardipine, Nifedipine, Nimodipine, Verapramil, Amlodipine, Nisodipine, Clevidipine, Lercandipine

Refer verapramil-

BEPRIDIL-

Generally not serious, rarely requires discontinuation or dosage adjustment

CNS -     Dizziness , 25%, Headache 13% Asthenia  13% Nervousness 11%,

               Tremor/hand tremor > 9%
               Drowsiness > 7%  Tinnitus 6%,Parathesia 2.5%, Insomnia 2.5%,

               Psychiatric disturbance,
               Depression, Amnesia, Paranoia, Psycosis, Hallucination, Anxiety,

               Blurred vision < 2%,

GASTROINTESTINAL -   Nausea 25%   Diarrhea  10% Hepatitis,

                                        Abdominal discomfort / cramps/ 

                                        dyspepsia 7%                                        

                                          Dry mouth/ thirst 3% Constipation   2% ,                                     
                                           Flatulence   < 2 %

CARDIOVASCULAR -   Palpitation   7 %, Peripheral edema , Bradycardia,

                                         Tachycardia < 2 %

DERMATOLOGIC-           Dermatitis/rash < 2 %

OTHER -                          Shortness of breath < 9%   Anorexia < 7%,

                                           Respiratory infection 3%
                                          Nasal or chest congestion, sinusitis, rhinitis, Sweating,

                                          sexual difficulties,  Cough < 2%

Refer - Verapramil- Calcium channel blockers

• Approved by FDA in December 1990

Indications:

Chronic stable angina

Dosage:

Individualise dosage. Usual initial dose is 200mg/day. After 10 days, dosage may be adjusted upward depending on response. Most patients are maintained at 300mg.

Maximum daily dose is 400mg, and minimum effective dose is 200mg.

Calcium Channel Blockers include -

Bepridil, Diltiazem, Felodipine, Flunarizine, Isradipine, Nicardipine, Nifedipine, Nimodipine, Verapramil, Amlodipine, Clevidipine butyrate, Lercanidipine

Refer verapramil-

Calcium channel blockers-

1.Take the medicine exactly as directed by the physician.

2.Swallow the tablet whole,without crushing or chewing it. However if advised by the doctor, you may break into half.

3.Take the medicine with food or milk.

Refer - Verapramil- Calcium channel Blocker

Take with food

Refer - Verapramil - Calcium channel blocker