Nitrates include Erythrityl tetranitrate, Isosorbide dinitrate, Isosorbide mononitrate, nitroglycerin , pentraerythritrol
  tetranitrate, glyceryl trinitrate
Refer - Isorbide 5- mononitrate


Postural hypotension potentiated with calcium channel blkrs, antihypertensives,phenothiazines,  
and tricylic antidepressants.Increases bioavailability of dihydroergometrines.
Alcohol causes hypotension and collapse.

 

Prophylaxis of angina

Nitrates include Erythrityl tetranitrate, Isosorbide dinitrate, Isosorbide mononitrate, nitroglycerin , pentraerythritrol
  tetranitrate, glyceryl trinitrate

Refer - Isorbide 5- mononitrate



 

Nausea,vomiting,headache,,apphrension,restlessness,weakness,vertigo and dizzines, tachycardia,palpitation and orthostatic hypotension.

Hypotension,hypovaemia,obstructive cardiomyopathy,M.I.  with right heart involvement.  Raised
intracranial pressure

Special precautions:
Glaucoma,mitral valve prolapse,renal/hepatic impairment.

 

Indications:
Prophylaxis of angina

Dosage:
Oral- 10 to  20mg 3 to 4 times a day. Titrate  to 40mg 4 times daily 1/2 hour before or 1 hour after meals.
Sustained release capsule- one capsule every 12 hours.

 

Nitrates include Erythrityl tetranitrate, Isosorbide dinitrate, Isosorbide mononitrate, nitroglycerin , pentraerythritrol  tetranitrate

Refer - Isorbide 5- mononitrate