Atenolol + Nifedipine- (FDC -List)Drug Name:
Atenolol + Nifedipine- (FDC -List)
List Of Brands:
Indication Type Description:
Dosages/ Overdosage Etc
Pregnancy and lactation
Increased risk of hypotension, and/or bradycardia, when used with catecholamine-depleting drugs If used clonidine, atenolol.an worsen rebound HTN following clonidine withdrawal
Hypotensive effect of atenolol is reduced when usedd with protagladin synthase inhibitors Nifedipine may incresae serum digoxin levels.
Cimetidine may increase peak plasma levels and area-under-curve of nifedipine
Reduced efficacy of nifedipine with phenytoin or rifampicin.
Calcium chan blockers may reduce clearance of nifedipine Increased plasma level of nifedipine with cisapride, quinupristin, or dalflopristin.
Concurrent use of nifedipine with MAOIs , nor-adrenaline or adrenaline may cause excessive increase in BP.
Cadiac depressants may be additive when used with narcotics or antiarrhythmics May potentiate action of non-deploarising muscle relxants
Headache, palpitation, flushing, depression,
wheezing, dizziness, hypotension,
GI upsets, fatigue, vertiigo,
warmth and swelling, Itching,
muscle cramps, and cold extremities
CCF , sinus bradycardia, heart block > 1st degree
Hypotension, overt cardiac failure,
Aortic stenosis, unstable angina, acute attacks of angina
Acute MI or secondary prevention of cardiogenic shock Lactation
Peripheral vascular disease, hepatic or renal dysfunction, malignant hypertension,
Fixed left ventricular obstruction. Withdrawal should be gradual
Execessive drop in BP may occur in some patients, especially elderly, when used in patients with airway obstruction.
Caution in diabetics as it may mask hypoglycemia
Continued depression of myo-cardium by beta blocker may lead to cardiac failures
Nifedipine may cause severe chest pain, increased severity duration or frequency of angina May mask signs of hypothyroidism
Not to be used in patients with untreated photochromocytoma
Caution when used in patients with peripheral circulatary disorders
Dosages/ Overdosage Etc:
Adults- atenolol 50mg + nifedipine sr 20mg 1 cap once or twice daily
Elderly- 1 cap once daily
Pregnancy and lactation:
Contraidicated for use during pregnancy and laction.