Drug Interaction:
Calcium Channel Blockers include -
Bepridil, Diltiazem, Felodipine, Isradipine, Nicardipine, Nifedipine, Nimodipine, Verapramil, Amlodipine, Nisodipine, Clevidipine, Lercandipine
Refer verapramil-
Single incidence of increased susceptibility to caffeine and phenytoin toxicity have been reported. May inhibit hepatic drug metabolism.
May enhance antihypertensive effects of cal channel blocking drugs which have more potent vasodilating properties.
Indication:
Subarachinoid haemorrhage.
Approved by FDA in December 1988
Approved by (DCI) Drug Controller GENERAL - India For Marketing
(Ref- IDMA Publication)
Name of Drug Indication Date of Approval
Nimodipine Cerebral protective August 1992
Calcium Channel Blockers include -
Bepridil, Diltiazem, Felodipine, Isradipine, Nicardipine, Nifedipine, Nimodipine, Verapramil, Amlodipine, Nisodipine, Clevidipine, Lercandipine
Refer verapramil-
Adverse Reaction:
Headache, muscle pain, dizziness, nausea, GI symtoms, fatigue, joint pain, flushing, hypotension, rash, constipation, changes in heart rate.
Contra-Indications:
Hypersens.
Special precautions:
Safety in pregnancy not established. Monitor pulse and B.P.during I.V.therapy. Reduce dose in patients with unstable B.P.
Dosages/ Overdosage Etc:
Approved by FDA in December 1988
Indications: Subarachinoid haemorrhage.
Dosage: 60mg every 4 hours for 21 consecutive days..
Patient Information:
Calcium Channel Blockers include -
Bepridil, Diltiazem, Felodipine, Flunarizine, Isradipine, Nicardipine, Nifedipine, Nimodipine, Verapramil, Amlodipine, Clevidipine butyrate, Lercanidipine
Refer verapramil-
Calcium channel blockers-
1.Take the medicine exactly as directed by the physician.
2.Swallow the tablet whole,without crushing or chewing it. However if advosed by the doctor, you may break into half.
3.Take the medicine with food or milk.
Pharmacology/ Pharmacokinetics:
Refer- Verapramil- calcium channel blockers
Interaction with Food:
Refer - Verapramil- Calcium channel blockers
Pregnancy and lactation:
Refer - Verapramil- Calcium channel blockers