Meptazinol- Opioid Analgesics- (BNF 68- 2015)
Drug Name:
Meptazinol- Opioid Analgesics- (BNF 68- 2015)
List Of Brands:
Indication Type Description:
Indication:
Moderate to severe pain, including postoperative and obstetric pain
and renal colic, perioperative analgesia
Adverse Reaction:
Side effects-
Can induce withdrawal symptoms in patients dependent on opioids
also diarrhea, abdominal pain, dyspepsia and hypothermia
Contra-Indications:
Cautions-
Effects only patially reveresed by naloxone
Contra-indication
Myocardial infraction, phaeochromocytoma
Hepatic impairment-
Opioid anagesics may precipitate coma in patients with hepatic impairment,
avoid use or reduce dose
Renal Impairment-
The effects of opioid anagesia are increased and prolonged and there is
increased cerbral sensitivity when patients with renal impairment are
treated with opioid analgesics, avoid use or reduce dose.
Dosages/ Overdosage Etc:
Indication-
Moderate to severe pain, including postoperative and obstetric pain
and renal colic, perioperative analgesia
Dose-
By mouth ,200mg every 3-6 hours as required
Child- Not recommended
By Inrtramuscular injection-
65-100mg every 2-4 hours if necessary,
obstertric analgesia, 100-150mg according to patients weight (2mg/kg)
Child- not recommended
By slow intravenous injection- 50-100mg every 2-4 hours if necessary
Child- Not recommended
Pregnancy and lactation:
Pregnancy-
Respiratory depression and withdrawal symptoms can occur in neonate if opioid
analgesics are used during pregnancy, also gastric statsis and inhalation
pneumonia has been reported in the mother if opioid anagesics are used
during labour.
Breast feeding -
Use only if potential benefit outweighs risk.