Flunarizine - @ Agents for Migraine- (Nov 1990)
Drug Name:
Flunarizine - @ Agents for Migraine- (Nov 1990)
List Of Brands:
Indication Type Description:
Pharmacology/ Pharmacokinetics
Drug Interaction:
Plasma levels reduced by phenytoin,carbamazepine,valproic acid.
Indication:
Migraine
Approved by (DCI) Drug Controller GENERAL - India For Marketing
(Ref- IDMA Publication)
Name of Drug Indication Date of Approval
Flunarizine Hcl Antimigraine November 1990
Adverse Reaction:
Drowsiness.Rarely weight gain, headache,depression, gastric pain,dry mouth,insomnia, extra-pyramidal reactions.
Contra-Indications:
Pregnancy,lactation.G.I./urinary tract obstruction. Special precautions: Driving or operating machinery,epilepsy,elderly.CVS disease,glaucoma.
Dosages/ Overdosage Etc:
Approved by (DCI) Drug Controller GENERAL - India For Marketing
(Ref- IDMA Publication)
Name of Drug Indication Date of Approval
Flunarizine Hcl Antimigraine November 1990
Migraine
Dosage-
10mg daily in single or two divided doses.
Children and patients below 40kg body weight - 5mg daily
Pharmacology/ Pharmacokinetics:
Not available
Interaction with Food:
Food has significant effect on oral 5-HT1 agonists bioavailability, but delays sumatriptans Tmax by aproximately 30 minutes and rizatriptans time to reach peak concentration by 1 hour. AUC and Cmax of eletriptan are increased approximately 20% to 30% following oral admin. of a high fat meal.
Pregnancy and lactation:
Excercise caution while using pregnancy and lactation