Enhances action of oxytocin,hence both drugs should be used sequentially and carefully monitored.

Action enhanced by prior injection of hyperosmolar urea.

Elective combination with mifepristone also lower side effects than when used alone.

Abortion,postpatrum utrerine bleeding.

Severe CVS disorders including fatal hypotension, tachyponea, pyrexia,and M.I. (in patients with high risk factors) following intra-aminiotic or intravaginal adminstration

Convulsions & ECG changes,amniotic fluid embolism and uterine rupture, foetal distress and rarely foetal death during induction of labour.

Nausea, vomiting, diarrhoea, abdominal pain, flushing, shivering, headache, dizziness, hypotension, temporary pyrexia.

Hypersens.Acute pelvic inflammatory disease.

Patients with acute cardiac,pulmonary,renal or hepatic disease.

Patients with H/O caesarian,major uterine surgery.

Special precautions:

Chorioaminonitis during labour may have an inhibitory effect on the uterine response to the drug. Hence not recocommended in this condition.

Concurrent admin of antiemetic and antidiarrhoeal drugs recommended to take care of adverse effect. Monitor patients with cardiopulmonary disorders,glaucoma,asthma.

Indications:

Abortion,postpatrum utrerine bleeding.

Dosage:

For IM use only. 250mcg(1ml) by deep IM injection. .Sequently 250mcg at 1.5 to 3.5 hour intervals.

Storage: Refrigerate at 2 to 4C. Stable for 9 days at room temp.

CARBOPROST-

1. Allergy- Tell your doctor if you are allergic to the medicine or any other oxytocics ( medicines that stimulate the urerus to contract ) or food substances, presrvatives, dyestuffs etc.

2. Other medicines- Tell your doctor if you are taking any of the following- Prescription medicines or OTC products

3. Other medical problems- Tell your doctor if you are having any other  medical problems-

Adrenal gland disease- carboprost stimulates the body to produce steroids Anemia- in some patients abortion with carboprost may resultin loss of blood that may require a transfusion.

Asthma- or Lung disease - carboprost may cause narrowing of the blood vessels in the lungs or narrowing of lung passages

Diabetes mellitus- or Epilepsy - rarely seizures have occured with use of carboprost

Glaucoma- rarely the pressure within the eye has increased during use of carboprost

Not available

Not reported.