NSAIDs include-

Propionic acid- Fenoprofen, Flurbiprofen, Ibuprofen, Ketoprofen, Naproxen, Naproxen Sodium,Oxaprozin

Acetic acids-  Diclofenac sodium, Etodolac, Indomethicin, Ketorolac, Nabumetone, Sulindac, Tolmetin
Fenamates (anthralic acids) - Meclofenamate, Mefenamic acxid
Oxicams- Piroxicam

Refer- Ibuprofen

Anticoagulants, sulphonylureas
Hydantoins, NSAIDs Aspirin

Probenecid, metoclopramide
Colestyramine, busulphan,Quinolone

Plasma protein bound drugs.
Lithium, antihypertensives, diuretics,

Cardiac glycosides, methotrexate, cyclosporin
Miferistone, corticosteroids,
Magnesium containing antacids
ACE  inhibitors or CYP2C6

Moderate to severe pain

GI  disturbances, (e.g abdominal pain, constipation, diarrheoa, nausea, dyspepsia, flatulance,
g-i ulceration  or bleeding )

Skin rash (discontinue )
Headache, pruritus, dizziness, oedema
Tinnitus, drowsiness, photosensitivity

CNS effects, alopecia, blurred vision
Renal, hepatic impairment, anaemia,

Thrombocytopenia
Raised liver enzymes

Allergic glomerulonephritis
Risk of cardiovascular events

Risk of hepatotoxicity among chronic heavy users
Hepatotoxicity (overdosages only )

Blood dyscrasias ( rare )

 

GI tract inflammation,
Glaucoma, peptic or gastric ulceration
Renal or hepatic impairment
Asprin/ NSAID allergy
Severe heart failure
Coronary artery bypass graft , surgery

Pregnancy lactation

Special precautions-
May exacerbate chronic urticaria or asthma
Dehydration
Haemoglobin and blood counts recommended
Elderly
Mild to moderate heart failure, epilepsy, asthma
Bleeding disorders,
Debilated , fliud retention,
Hypertension
Monitor for G-I ulcer bleed ( risk is increased if patient is otherwise at high risk ),
extended drug treatment, high doses, smokers, alcoholics, history of GI bleed or ulcer)
Blood , renal ,hepatic and ocular function in chronic use
Labour and delivery

 

Moderate to severe pain

1 tablet thrice daily

NSAIDS INFORMATION INCLUDES-
     
           DICLOFENAC, DIFUNISAL, ETODAC, FENOPROFEN, FLOCTAFENINE, FLURBIPROFEN, IBUPROFEN,
           
           INDOMETHICIN, KETOPROFEN, MECLOFENAMATE, MEFENAMIC ACID, NABUMETONE, NAPROXEN,
           
            OXAPROZIN,PHENYLBUTAZONE, PIROXICAM, SULINDAC, TENOXICAM, TIAPROFENIC, TOLMETIN

             REFER - IBUPROFEN


Mefanamic acid
------------------------
1. NSAIDs  can cause  discomfort and rarely more serious side effects such as GI bleeding which
    may result in hospitalisation and even fatalities.
2.Avoid aspirin and alcoholic beverages while taking medication.
3. If GI upset occurs, take with food, milk or antacids. For GI upset with tolmetin, use antacids other     than sodium bicarbonate.
4. Notify physician, if skin rash, itching, visual disturbances, weight gain, edema occurs
5. Mefanamic acid and metclofenate: if rash, diarrhoea, or digestive problem occur discontinue      use  and consult physician
6. Ibuprofen- Do not take for more than 3 days for fever or 10 days for pain. If these symptoms    persists,consult a physican.

 

 Contraindicated for use during pregnancy and lactation
Observe caution if requried to be used