Alcohol or CNS depressants eg barbiturates, narcotics- exaggerated  depression effects will
occur when used concomittantly.
Anticoagulants oral- Ethchlovynol may decreae the hypoprombinemic effect of the anti-coagulant.
Dosage adjustment may be required at initiation  and discontinuation  of therapy

Hypnotic - short term use

Vomiting, gastric upset, nausea, aftertaste. Dizziness, facial numbness. Thrombocytopenia.
Cholestatic jaundice, urticaria, rash. Blurred vision, hypotension, hangover.

Hypersensitivity, porphyria.

Special precautions:
CNS effect- do not use for management of insomnia in presence of pain. Performing hazardous tasks, tartrazine sensitivity

 

Indications:
Hypnotic - short term use

Dosage:
Usual dose is 500mg at bed time. 750mg may required for some patients whose response to
500mg is inadequate or for patients being changed from barbiturates or nonbarbiturate hypnotic

1. May cause drowsiness,dizziness, blurred vision, observe caution while driving or performing   other tasks requiring alertness.

2. Avoid alcohol and other CNS depressants. Do not exceed prescribed dosage.

3. Symtoms of giddiness, ataxia or GI upset may be reduced if the drug is taken with food.

4.Allergies-
   Tell your doctor if you have ever had any unusual or allergic reaction to ethchlovynol or related  products.
   Also tell your doctor if youare allergic to any other substances, such as foods, presrvatives or dyes.   

5.Pregnancy -
   Ethclorvynol has not been studied in  pregnant  women. However use of  ehthchlorvynol  during the  first 6 mths  of  is not recommended because  studies in animals  have shown that  high doses of    ethchlorvynol increase chances  of still births and decrease the cance of  newborn from surviving .
    Taking ethchlorvynol  during 6 mths of  pregnancy  may cause  slow heart beat, shortness of breath ,  troubled breathing  or wthdrawal side effects  in the new born
   baby.   
    
6.Breast feeding-
   It is not known whether chlorvyol  pases into  breast milk
 
7 Children -
  Studies done only in adults patients and there is no specific information comparing the use of  chlorvynol in children with use in other age groups

8. Elderly-
    May increase the chance of side effects during treatment

9. Other medicines -

    Let your doctor know what other medicines you are taking any of the following,  so that he can advice you   accordingly.
   
    Anticoagulants - ethchlorvynol  may change the amount of anticoagulant you need to take
    
   Central Nervous System CNS depressants- or
   Tricyclic antidepresants - using these medicines together may increase the CNS and other
    depressants effects.

       
11. Other medical problems -

   Tell your doctor if you have any other medical problems especially -

    Alcohol abuse or
    Drug abuse  ordependence  - dependenc of  ethchlovynol  may develop
    
     Kidney disease  or
     Liver disease - higher bloodlevels  ofethchlovynol  may result and increae  the chance of      side  ffects.
           
      Mental depression  or
      Porphyria - ethchlorvynl  may make the condition worse
       
12. Missed dose -
      If you miss a dose of this medicine, take it as soon as possible. however, if it is almost         time  for the next dose, skip the missed dose. Do not double doses.

13. Storage -
      Keep out of reach of children. Store away from heat or direct sunlight. Do not store
      the capsule in bathroom, near the kitchen sink, or in other damp places.

14. Outdated medicines -
     Do not keep outdated medicine or medicine no longer needed. Be sure that any
     discarded medicine is out of reach of children.

 

Pharmacology:
Ethchlorvynol has a seadative-hypnotic, anti-convulsant and muscle relaxant properties. It
produces EEG patterns similar to those produced by barbiturates.

Pharmacokinetics:
Rapidly absorbed from GI tract, peak plasma concentration occur within 2 hours after a single
oral fasting dose. Within 24 hours,33% of a single 500mg dose is excreted in the urine as
metabolites

 

May be taken with food

Pregnancy:
Use only if needed.

Lactation:
Use with caution when administering to a nursing mother.