Moderate to severe pain.


 

Respiratory depression,shock. Dysphoric reactions,toxic psychosis,convulsions.
 Nausea, vomiting,constipation,
Urinary retension,
Headache,anxiety,
Hyperthermia or hypothermia,
Pruritus, wheals, urticaria,
Tachycardia, bradycardia,
Syncope changes in blood pressure, muscle tremor,  
Blurred vision,  
Nystagmus, miosis, dependency.

 

Respiratory depression,paralytic ileus,delayed gastric emptying,
Obstructive airways  disease,
Acute liver disease,morphine sensitivity.  
Use with MAO inhibitors concomittantly or 2 weeks after stopping them.
Pregnancy and lactation, children.

Special precautions:
Elderly,
Hyperthyroidism,
Renal and chronic liver disease,suspected paralytic ileus,
Head  injury, intracranial lesions or pre-existing increase in intracranial pressure,
Hypotension,  circulatory shock,
Seizure-prone patients.

 

Indications:
 Moderate to severe pain.

Dosage:
Oral administration is 1/2 to 1/6 as effective as parentral administration.
Oral - 10 to 30mg every  4 hours
Controlled release- 30mg every  8 to 12 hours
IV- Adults- 2.5 to 15mg/70kg in  4 to 5ml of  water for injection,administered  over 4 to 5 minutes.

 

1.May cause drowsiness,dizziness or blurring of vision. Use caution while driving or performing
  tasks requiring alertness.

2.Avoid alcohol and other CNS depressants.

3.Notify physician if nausea,vomiting or constipation become prominent.

4.If GI uo\pset occurs,these agents may be taken with food.

5.Notify physician,if shortness of breath or difficulty of breathing occurs.

 

- REFER DEXTROPROPOXYPHENE

Not reported

Pregnancy:
Safety for use during pregnancy has not been established. Use with extreme caution.

Lactation:  
These agent appear in breast milk. use with exteme caution.