Indication:
As per US FDA guidelines as per USPDA 1997
It is the intention to bring out the salient features. Hence relevent details as prescribed by US FDA guidelines as per USPDA 1997 are brought out clearly in the following chapters.
Descriptons are detailed only to the Group Head and the indiviual items can be seen by visiting the Web Site
ANTIDOTE-
Antidote to Acetaminophen overdose- Racemethionine
Antidote - adsorbent- Charcoal, Activated (oral
Antidote- adsorbent laxative-- Charcoal, Activated and Sorbitol )oral
Antidote, anion exchange resin- Cholestyramine (oral)
Antidote to beta-adrenergic blocking agents- Glucagon(systemic)
Antidote to calccium channnel blocking agents- Glucagon (systemic)
Antidote to cholinestrarase inhibitors- Atropine(systemic), Hysocyamine (systemic)
Antidote to cynanide poisioning- Amyl Nitirite (systemic) Sodium Thiosulfate (systemic)
Antidote to cycloserine poisioning- Pyridoxine (vitamin B6) (systemic)
Antidote to dipyridamole toxicity- Aminiophylline (systemic)
Antidote to drug induced hypoprothrombinnemia- Menadiol (systemic) Phytonadione (systemic)
Antidote to ergot alkaloid poisioning- Prazosin (systemic)
Antidote to folic acid antagonists- Leucovorin (systemic)
Antidote to heavy metals- Penicilliamine (systemic)
Antidote to isoniazid poisioning- Pyridoxine (vitamin B6 (systemic)
Antidote to muscarine- Atropine (systemic) Hyoscayamine (stystemic)
Antidote, to nondepolrizing nueromuscular block- Neostigmine (systemic) Pyridostigmine (systemic)
Antidote , to organophosphate pesticides- Atropine (systemic)
Cycloplegic mydriatic include- Opthalmic
Atropine sulphate, homatropine Hbr, Scoplolamine Hbr, Cyclopentolate,Tropicamide
Refer - Homotropine Hbr
1. To avoid contamination, do not touch dropper tip to any surface. Replace cap after using.
2. May cause blurred vision. Do not drive or engange in any hazardous activites while pupils are dilated.
3. May cause sensitivity to light. Protect eyes in bright illumination during dilation.
4. Keep out of reach of children. These drugs should not be taken orally. Wash your hands and the childs following administration.
5. If eye pain occurs, discontinue use and consult physician immediately.
6.Allergies-
Tell your doctor if you have ever had any unusual or allergic reaction to atropine,
homatropine, or scopolamine. Also tell your doctor if you are allergic to any other
substances, such as certain preservatives.
7.Pregnancy-
Studies on effects in pregnancy have not been done in either humans or animals.
however, these medicines may be absorbed into the body.
8.Breast -feeding-
These medicines may be absorbed into the body. Atropine passes into the breast
milk in very small amounts and may cause side effects , such as fast pulse, fever,
or dry skin, in babies of nursing mothers using optlamic atropine. It is not known
whether homatropine, or scoplolamine passes into breast milk in small amounts,
many of them may be used safely while breast-feeding.
Mothers who are using one of these medicines and who wish to breast feed should
discuss with their doctor.
9.Children-
Infants and young children with blond hair or blue eyes may be especially sensitive
to the effects of atropine, hemotropine, or scopolamine. This may increase the
chance of side effects.
10.Elderly-
Elderly people are especially sensitive to the effects of atropine, homotropine,
scopolamine. This may increase the chance of side effects during treatment
11.Other medicines -
Although certain medicines should not be used together at all, in other cases two
different medicines may be used together even if an interaction might occur. in such
cases your doctor may want to change the dose, or other precautions may be necessary.
Tell your health care professional if you are taking any other prescription or
non-prescription ( over -the-counter ) OTC medicine
12.Other medical problems-
The presence of other medical problems may affect the use of ophthalmic atropine,
homotropine or scopolamine. Make sure that you tell your doctor if you have any
other medical problems especially-
Brain damage( in children) or
Downs syndrome(monogolism) in children and adults) or
Glaucoma or
Other eye diseases or problems or
Spastic paralysis( in children) - use of opthalmic atropine, homotropine,
or scopolamine may make the condition worse.
