As per US FDA guidelines as per USPDA 1997

It is the intention to bring out the salient features. Hence relevent details as prescribed by US FDA guidelines as per USPDA 1997  are brought out clearly in the following chapters. 

Descriptons are detailed only to the Group Head and the indivdual items can be seen by visiting the Web Site

ANTIEMETIC-

Buclizine (systemic)                                                                                                          Chlorpromazine (systemic)                                                                                              Cyclizine (systemic)                                                                                                          Dimenhydrinate (systemic)                                                                                              Diphenyhydramine (systemic)                                                                                          Diphenidol (systemic)                                                                                                        Fructose, Dextrose, and Phosphoric acid (oral)                                                            Granisetron (systemic)                                                                                                    Meclizine (systemic)                                                                                                          Metclopromide (systemic)                                                                                                Nabilone (systemic)                                                                                                          Ondensetron (systemic)                                                                                                    Perohenazine (systemic)                                                                                                  Prochlorperazine (systemic)                                                                                            Promethazine (systemic)                                                                                                  Scopolamine (systemic)                                                                                                  Triethylperazine (systemic)                                                                                              Triflupromazine (systemic)                                                                                              Trimethobanzamide (systemic)

Antiemetic in Cancer Therapy-                                                                                        Corticotropin- Gluccocorticoid effects (systemic)                                                        Dexamethazone- Gluccocorticoid effects (systemic)                                                    Hydrocortisome -Gluccocorticoid effects (systemic)                                                    Lorazepam -(systemic)                                                                                                      Prednisone-Gluccocorticoid effects (systemic)                                  

Antiemetic- drug-related-                                                                                                  Domperidone - (systemic)       

Refer Chlorpromazine

1. May cause drowsiness,use caution while driving and performing tasks requiring alertness,physical coordination and dexterity.

2. Phenthizines- Avoid prolonged exposure to sunlight.

3. May discolour the urine pink or reddish brown.

4.Allergies- tell your doctor if you have ever had any unusual or allergic reaction to phenothiazines Also tell your doctor if you are allergic to any other substances, such as foods, presevatives or dyes.

5.Pregnancy - studies in animals have shown that chlorpromazine and trifluroperazines given in many times the human dose may cause birth defects.

6.Breast feeding- phenothiazines pass into breast milk and may cause drowsiness and greater chance of unusual muscle movement in the nursing baby

7. Children - certain side effects such as muscle spasms of the face , neck, and back aremore likely to occur in children

8.Elderly- are more sensitive than younger adults to the side efects of phenothiazines

9. Other medicines - Amantadine or Antihypertensives or Bromocriptine or Dexaferoxamine or Diuretics or Levobunolol or Medicine for heart disease or Metipranolol Nabilone or Narcotic pain or Nimodipine or Other antipsychotics or Pentamidine or Pimozide or Promethazine or Trimeprazine - severe low blood pressure may occur

10. Other medical problems - Tell your doctor if you have any other medical problems especially - Alcohol abuse - certain side effects such as heat stroke may be more likely to occur Blood disease or Breast cancer or Difficult urination or Enlarged prostrate or Glaucoma or Heart or blood vessel disease or Lung disease or Parkinsons disease or Seizure disorders or Stomach ulcers - phenothiazines may the conditon worse

11. Missed dose - If you miss a dose of this medicine, take it as soon as possible. however, if it is almost time for the next dose, skip the missed dose. Do not double doses.

12. Storage - Keep out of reach of children. Store away from heat or direct sunlight. Do not store the capsule in bathroom, near the kitchen sink, or in other damp places.

13. Outdated medicines - Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of reach of children.

14. AVOID CONCURRENT USE WITH ERYTHROMYCIN