Benzodiapines include-

Alprozolam, Chlordiazepoxide, Clonazepam, Clorazepate,Diazepam, Halazepam, Lorazepam, Oxazepam, Prazazepam

Refer Diazepam 

Anticonvulsants include- 

Barbiturates, oxazolidinediones, Miscellanous

Phenobarbitone -Paramethadione Lamotrigine Trimethadione Primidone

Hydantions - Valproic acid Phenytoin

Benzidiazepines- Cabamazepine Mephenytoin Clonazepam Phenacemide Ethotoin Clorazepate Felbamate Diazepam Gabapentin

Succinimides - Ethosuximide Methsuximide Phensuximide

Refer Phenytoin -

Benzodiapines include-

Alprozolam, Bromozepam, Chlordiazepoxide, Clonazepam, Clorazepate,Diazepam, Estazolam, Flurazepam, Halazepam, ketazolam,Lorazepam,Nitrazepam, Oxazepam, Prazepam, Quazepam, Temazepam, Triazolam

Refer  Diazepam

Drug interation- summary

+ Clonazepam

 Barbiturate

increased clonazepam clearance occur, leading to lower steady-state levels and loss of efficacy

 Valproic acid +Clonazepam or Clonazepam + Valproic acid

  increased toxicity (drowsiness ) of clonazepam, reduced efficacy of both drugs 

Adjunct treatment of lennox-gastaut syndrome(petit mal variant),a kinetic and myoclonic seizures.  

Benzodiapines include-

Alprozolam, Bromozepam, Chlordiazepoxide, Clonazepam, Clorazepate,Diazepam, Estazolam, Flurazepam, Halazepam, ketazolam,Lorazepam,Nitrazepam, Oxazepam, Prazepam, Quazepam, Temazepam, Triazolam

Refer  Diazepam

Anticonvulsants-  Refer Phenytoin

Hypotension,apnoea,may be very serious when combined with alcohol,

Rare blood dyscrasias, thrombocytopenia.

Drowsiness, somnolence, fatigue, muscular hypotonia,

co-ordination disturbances, dizziness,

vertigo, anorexia, dyspepsia,visual and sleep disturbances,

loss of libido, impotence, abnormal thirst,

skin pigmentation,rashes and facial oedema.

Hypersens to benzodiazepine,acute pulmonary insufficiency,

respiratory depression,lactation and pregnancy.

Special precautions:

Neonates,chronic pulmonary insufficiency,impairment of hepatic renal function, porphyria,elderly.

Date of Approval    1995

Indications:

Adjunct treatment of lennox-gastaut syndrome(petit mal variant),

a kinetic and myoclonic seizures.

Dosage:

Initial - not to exceed 1.5mg/day in 3 divided doses.

Increase in increment of 0.5 to 1mg every 3 days until seizures are adequately controlled. Maximum recommended dose is 20mg/day.

Children -(upto 10 yearss age)- initial -0.01 to 0.03mg/kg/day.

Not to exceed 0.05mg/kg/day in 2 or 3 divided doses.

Benzodiapines include-

Alprozolam, Bromozepam, Chlordiazepoxide, Clonazepam, Clorazepate,Diazepam, Estazolam, Flurazepam, Halazepam, ketazolam,Lorazepam,Nitrazepam, Oxazepam, Prazepam, Quazepam, Temazepam, Triazolam

Refer  Diazepam   Anticonvulsants - refer Phenytoin

Refer Diazepam  Anticonvulsants - Refer Phenytoin

Pharmacology:

Clonazepam is a benzodiapine, is an efective anticonvulsant. It raises the threshold for propagation of seizure activity and prevents generalisation of focal or local activity.

Take with or without food
 

Observe caution if required to be administered during pregnancy and lactation