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Enzymatic zonulysis for intracapsular extraction

Severe allergic reactions following intramuscular admin.

Ophthalmological -Increased intraoccular pressure corneal odema, striation and uvetitis following opthalmic use.

Hypersentivity to or any component of the preparation

High vitreous pressure; gaping incisional wound,

congenital catarats, patients less than 20 years old due to probable lens-vitreous adhesion not responsive to alpha - chymotrypsin lysis

Indications:

Enzymatic zonulysis for intracapsular extraction

Dosage- 

1 tab 4 times daily before meals

Pharmacology:

Chymotrypsin is a proteolytic enzyme. The principal proteolytic effect is exerted by splitting of peptide bonds of amino acids in zonular fibers and ocular tissues.

Pharmacokinetics:

Destruction of the equatorial pericapsular membrane of the lens occurs in 5 minutes. Zolar fibers are lysed within 10 to 15 minutes of application; complete lysis of the entire membrane occurs in 30 minutes.