Drug Information

Updated On: 27-02-2024

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Chlormezanone- @ Skeletal muscle relxant

Drug Name:
Chlormezanone- @ Skeletal muscle relxant

List Of Brands:

DOLOBAK

Indication Type Description:

Drug Interaction

Indication

Adverse Reaction

Contra-Indications

Dosages/ Overdosage Etc

Other Information

Patient Information

Pharmacology/ Pharmacokinetics

Interaction with Food

Pregnancy and lactation

Drug Interaction:

Skeletal Muscle Relaxant include-

Carisprodal, Chlorphenesin Maleate, Chlorzoxazone, Chlormezanone, Cyclobenzaprine, Methocarbinol, Metaxalone, Dantrolenes Sodium, Orphenadrine.

Refer Orphenadrine

Alchohol and CNS depressants - possible additive CNS effect may occur

Indication:

Mild anxiety and tension states.

Skeletal Muscle Relaxant include-

Carisprodal, Chlorphenesin Maleate, Chlorzoxazone, Chlormezanone, Cyclobenzaprine, Methocarbinol, Metaxalone, Dantrolenes Sodium, Orphenadrine.

Refer Orphenadrine

Adverse Reaction:

Drug rash,dizziness, flushing, nausea,drowsiness,

Depression, edema, dry mouth,

Weakness, excitement,

Tremor, confusion, headache.

Contra-Indications:

Hypersensitivity to chlormezanone

Special precautions:

Should drowsiness occur,reduce dose.

Patients should observe caution while driving or performing tasks which require mental alertness.

Dosages/ Overdosage Etc:

Indications:

Mild anxiety and tension states.

Dosage:

Adults - 200mg 3 or 4 times /day. In some cases 100mg may suffice.

Children(5 to 12years)- 50 to 100mg 3 or 4 times/day..

Other Information:

For Availability/supplies

Contact -

1.Indian Drug Manufacturers Association (IDMA)

Phone- 022- 24944624/ 24974308

Fax- 022- 24950723

Email- idma@vsnl.com

Website: www.idma-assn.org

2.Bulk Drug Manufacturers Association (India)(BDMA)

Phone - 040-23703910/ 23706718

Fax- 040-23704804

Email- info@bdmai.org

Website: www.info@bdmai.org

Patient Information:

Skeletal Muscle Relaxant include- Carisprodal, Chlorphenesin Maleate, Chlorzoxazone,

Chlormezanone, Cyclobenzaprine, Methocarbinol, Metaxalone, Dantrolenes Sodium,

Orphenadrine.

Chlormezanone - Systemic

1.The drug may impair the mental or physical abilities required for the performance of

potentially hazardous tasks such as driving or operating machinery.

2.Avoid alcohol with the drug.

3.Notify physician if skin rash, sore throat or fever occurs.

4.Allergies-

Tell your doctor if you are have ever had any unusual or allergic reaction to

chlormezanone. Also tell your healthcare care professional if you are allergic

to any other substances such as foods. preservatives or dyes.

5.Pregnancy-

Studies have not been done in humans or animals

6. Breast-feeding-

Chlormezanone has not been reported to cause problems in nursing babies.

7.Children-

Although there is no specific information comparing use of chlormezanone

in children with use in other age groups.this medicine is not expected

to cause different side effects or problems than it does in adults.

8.Older adults-

Many medicines have not been studied specifically in older people. Therefore,

it may not be known whether they work exactly the same way they do in

younger adults, or if they cause different side effects or problems in older people.

Although there is no specific information comparing use of chlormezanone

in the elderly with use in other age groups is not expected to cause different

side effects or problems than it does in younger adults.

9. Other medicines-

Although certain medicines should not be used together at all, in other cases two

different medicines may be used together even if an interaction might occur.

In such cases your doctor may want to change the dose, or other precautions

may be necessary.

When you are taking chlormezanone it is especially important that your doctor

know if you taking any of the especially-

Central nervous system CNS depressants(medicines that causes drowsiness) or

Tricyclic antideporessants( medicines for depression) - concurrent use may

increase CNS depressant effects of either these medications

or chlormezanone

7. Other medical problems-

The presence of other medical problems may affect the use of chlomezanone.

Make sure you tell your doctor if you have any other medical problems

especially-

Drug absuse or dependence ( or history of) - dependence on chlormezanone

may develop.

Kidney disease or

Liver disease- higher blood levels or chlormezanone may occur, increasing

the chance of side effects

Pharmacology/ Pharmacokinetics:

Pharmacology:

Chlormezanone improves the emotional state by allaying mild anxieties usually without impairing clarity of consciousness. The mechanism of action is unknown.

Phamacokinetics:

The relief of symptoms is often apparent 15 to 30minutes after administration and may last 6 hours or longer. Peak plasma concemtrations are attained within 1 to 2 hours; mean elimination half-life is 24 hours.

Interaction with Food:

Reports not available

Pregnancy and lactation:

Safety for use of drug during pregnancy or lactation has not been established.

Use only when clearly needed, when the potential benefits outweigh the potential hazards to the fetus.

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