Decreases effect of tricyclic antidepressents, hypoglycaemic agents, anticoagulants.

Rifampicin, barbiturates and phenytoin may interfere with effects.

Threatened miscarriage

Menstrual irregularities and amenorrhoea with prolonged use.

GI disturbances, Acne, fluid retension and oedema,

Weight gain, allergic reactions,

Mental depression,

Breast discomfort,

Changes in libido,

Altered LFT,

Jaundice(rare).

History of thomboembolic disorders.

Mammary or genital carcinoma.

Liver dysfunction.

Undiagnosed abnormal uterine bleeding.

Special precaution:

Diabetes, epilepsy, migraine.

Indication-

Threatened miscarriage

Dosage-

Adult - 5mg tid for 5- 7 days

May be taken with meals if GI upset occurs

May be taken with meals if GI upset occurs