Oestrogens

Endometriosis Uterine fibroidsprior to surgery or when surgery is not possible

Hot flushes, menorrhalgia Spotting, sweating,vaginal dryness Dyspareunia, decreased libido, mood changes Sleep disturbances, nausea, rash, Weight gain, transcient sight disturbances, Myalgia, asthenia, odema Arthalgia, reversible bone loss, Injection site reactions, phlebitis, Transcient hypertension, Pituitary apoplexy, hyperglycemia, Increased risk of diabetes, Increased risk of myocardial infarction, Sudden cardiac death and stroke, Rarely, vertigo, G I disturbances, Gynaecomastia, hair loss, headche, Fever, dysuria,

Pregnancy, Non-hormonal methods of contraception must be used. Lactation Special precautions- Metabolic bone disease

  Anti-cancer                            

Endometriosis Uterine fibroids prior to surgery or when surgery is not possible

Start during first 5 days of menstrual cycle Endometriosis-

Dosage-

One vial by i.m. injection every 28 days for maximum 6 months Fibroids- One vial by i.m. injection every 28 days for minum 3 months

Consider uterine lelomyosarcoma if no change or an increase in uterine volume Children - not applicable

Contraindicated for use during pregnancy and lactation Observe caution