Drug Interaction:
Penicillins include-
Natural- Penicillin G, Penicillin V
Penicillase -Resistent- Cloxacillin, Docloxacillin, Methicillin, Nafacillin, Oxacillin
Aminopenicillins- Amoxicillin, Amoxicillin/Potassium Clavulanate, Ampicillin, Ampicillin/Sulbactum, Becampicillin
Extended spectrum- Carbenicilin, Mezlocillin, Piperacillin.Tazobactam sodium, Ticarcillin, Ticarcillin/Potassium clavulanate
Refer Penicillin V Potassium
Hypokalaemia may be hazardous if digitalis is administered concomittantly. Effective combination in high doses with aminoglycosides in psuedononas infection. Probenecid prolongs half-life of carbenicillin.
Indication:
Penicillins include-
Natural- Penicillin G, Penicillin V
Penicillase -Resistent- Cloxacillin, Docloxacillin, Methicillin, Nafacillin, Oxacillin
Aminopenicillins- Amoxicillin, Amoxicillin/Potassium Clavulanate, Ampicillin, Ampicillin/Sulbactum, Becampicillin
Extended spectrum- Carbenicilin, Mezlocillin, Piperacillin.Tazobactam sodium, Ticarcillin, Ticarcillin/Potassium clavulanate
Refer Penicillin V Potassium
Adverse Reaction:
Prolongation of bleeding time in high doses.
Granulocytopenia, phlebitis at site of injection. Hypokalemia.
Contra-Indications:
Known history of penicillin hypersens.
Special precautions:
Except in renal impairment recommended dosages should be reduced.
Admn at less than full dose may permit multipication of resistent strains, especially pseudomonas.
Where renal function is impaired, dose may be reduced.
Monitoring is advised in such cases to ensure that adequate serum antibiotic concentrations are maintained.
Patients with haemorrhagic diasthesis of severe cardiac insufficiency.
Dosages/ Overdosage Etc:
Indications:
Lower and upper respiratory infections
Dosage:
382 to 764mg 4 times/day.
Missed dose-
1. If you miss a dose of this medicine take it as soon as possible. This will help to keep a constant amount of medicine in the blood or urine.
2. However, if it is almost time for your next dose skip the next dose and go back to your regular dosing schedule.
3. Do not double doses.
Other Information:
For Availability/supplies
Contact -
1.Indian Drug Manufacturers Association (IDMA)
Phone- 022- 24944624/ 24974308
Fax- 022- 24950723
Email- idma@vsnl.com
Website: www.idma-assn.org
2.Bulk Drug Manufacturers Association (India)(BDMA)
Phone - 040-23703910/ 23706718
Fax- 040-23704804
Email- info@bdmai.org
Website: www.info@bdmai.org
Interaction with Food:
Reports not available