Cefadroxil - Cephalosporins @ - First generation- (FDC-List) (Feb 1989)
Drug Name:Cefadroxil - Cephalosporins @ - First generation- (FDC-List) (Feb 1989)
List Of Brands:
Indication Type Description:
Drug Interaction
Indication
Adverse Reaction
Contra-Indications
Dosages/ Overdosage Etc
Other Information
Patient Information
Pharmacology/ Pharmacokinetics
Interaction with Food
Pregnancy and lactation
Drug Interaction:
Drugs covered:
1st generation 2nd generation 3rd generation .
Cephalexin Cefaclor Cefixime Cefadroxil Cefamandole Cefoperazone Cephadrine Cefotoxitin Cefotaxime Cephalothin Cefuroxime Ceftizoxime Cephapirin Cefonicid Ceftriaxone Cefazolin Cefmetazole Ceftazidime Cefotetan Ceftibuten Cefprozil Cefepime Cefpodoxime Loracarbef
Refer Cephalosporins
Concurrent use with frusemide increases risk of nephrotoxicity.
Potentiates nephrotoxicity of aminoglycosides.
Prothrombin time prolonged, caution necessary with anticogulants.
Probenecid prolongs half-life.
Indication:
U.S.FDA APPROVED DRUGS FROM 01-01-08 TO 31-12-08
U.S FDA APPROVED DRUGS DURING 2006
1st generation 2nd generation 3rd generation .
Cephalexin Cefaclor Cefixime Cefadroxil Cefamandole Cefoperazone Cephadrine Cefotoxitin Cefotaxime Cephalothin Cefuroxime Ceftizoxime Cephapirin Cefonicid Ceftriaxone Cefazolin Cefmetazole Ceftazidime Cefotetan Ceftibuten Cefprozil Cefepime Cefpodoxime Loracarbef
Refer Cephalosporins
A First generation drug
Adverse Reaction:
Anaphylactic reactions.
Nausea,vomiting, diarrhoea, abdominal discomfort.
Allergic reactions such as skin rash, urticaria, eosinophilla, angioedema. Rise in liver enzyme values.
Superinfection with resistent organisms(esp candida) Possibility of pseudomembranous colitis.
False urinary reaction of urinary glucose, development of positive coombs test.
Interferes with cross matching of blood.
False positive precipitation test with proteins.
Contra-Indications:
Known allergy to cephalosporins.
Special precautions:
If hypersen reactions occur, discontinue drug & treat suitably.
Prolonged use may cause over-growth of non-suseptible organisms.
If superinfection occurs take appropiate measures.
Caution in patients with history of GI disease especially colitis.
Dosages/ Overdosage Etc:
A first generaration drug.
Indications:
Urinary tract infection, skin & skin structure infections, pharyngitis, tonsilitis.
Food interaction: Can be given without regards to meals.
Dosage:
1 or 2g/day in single or divided doses.
Children: 30mg/kg/day in divided doses every 12 hours..
Other Information:
Patient Information:
Refer cephalosporins
Pharmacology/ Pharmacokinetics:
Refer cephalosporins
Interaction with Food:
Can be given without regards to meals.
Pregnancy and lactation:
Refer cephalosporins
