Drugs covered:

1st generation 2nd generation 3rd generation . Cephalexin Cefaclor Cefixime Cefadroxil Cefamandole Cefoperazone Cephadrine Cefotoxitin Cefotaxime Cephalothin Cefuroxime Ceftizoxime Cephapirin Cefonicid Ceftriaxone Cefazolin Cefmetazole Ceftazidime Cefotetan Ceftibuten Cefprozil Cefepime Cefpodoxime Loracarbef

Refer Cephalosporins

Renal clearance reduced by probenecid. Activity may be reduced by chloramphenicol. Interference with copper reduction method of testing glycosuria.

A third generation drug.

Approved by (DCI) Drug Controller  GENERAL -  India  For Marketing                                                                                                            (Ref- IDMA Publication)

Drugs covered:

1st generation 2nd generation 3rd generation . Cephalexin Cefaclor Cefixime Cefadroxil Cefamandole Cefoperazone Cephadrine Cefotoxitin Cefotaxime Cephalothin Cefuroxime Ceftizoxime Cephapirin Cefonicid Ceftriaxone Cefazolin Cefmetazole Ceftazidime Cefotetan Ceftibuten Cefprozil Cefepime Cefpodoxime Loracarbef

Refer Cephalosporins

Anaphylactoid reactions.

On injection, burning, induration, tenderness, paraesthesia, phlebitis and cellulitis. Hypersens reactions.

Rash, pruritus or fever. Anorexia, nausea, vomiting, diarrhoea, rarely neutropenia, leucopenia and thrombocytopenia.

Transcient elevation of transaminases (SGOT and SGPT) and alkaline phosphatase, Transient rise in BUN and creatinine.

Renal impairment, Htpensens to penicilins

Special precautions: Reports not available

A third generation drug.

Indications: Lower respiratory infections, urinary tract infections, gonorrhoea, pelvic inflamatory disease, intra-abdominal infections, septicaemia, skin and structure infections, bone & joint infections, meningitis.

Dosage: 1 to 2g every 8 to12 hours.

Children- More than 6mths - 50mg/kg every 6 to 8 hours. Dosage may be increased to 200/kg/day . Do not exceed the maximum adult dose for serious infection.

Storage: After reconstitution or dilution, solutions are stable for 24 hours or at temperature for 96 hours if reffrigerated at (5C. 41F).

For Availability/supplies 

Classifiaction: Antibiotic.

Patent position: Patent expires 13TH March, 1998

Major Brands:

CEFIZOX

GLAXO-WELLCOME

EPOCELIN RALLIS

Refer cephalosporins

Refer cephalosporins

Refer cephalosporins

Refer cephalosporins