Drugs covered:

1st generation 2nd generation 3rd generation . Cephalexin Cefaclor Cefixime Cefadroxil Cefamandole Cefoperazone Cephadrine Cefotoxitin Cefotaxime Cephalothin Cefuroxime Ceftizoxime Cephapirin Cefonicid Ceftriaxone Cefazolin Cefmetazole Ceftazidime Cefotetan Ceftibuten Cefprozil Cefepime Cefpodoxime Loracarbef

Refer Cephalosporins

Interacting drugs - summary

Cefotetan +

Ethanol incr Alcoholic beverages consumed concurrently with or upto 72 hours after cefamandole, cefaperazone,moxalactum, or cefotetan produce acute alcohol intolerance(disulfram-like reaction). The reaction begins within 30 minutes after alcohol ingestion and may subside 30 minutes to several hours afterwards

Anticoagulants incr Hypoprothrombinemic effects of anticoagulants be increased by cephalosporins (cefamandole, cefoperazone, cefotetan, moxalactum). Bleeding complications occur. The concurrent use of heparin also theoritically increase the risk of bleeding.

Cefotetan +

Ethanol incr Alcoholic beverages consumed concurrently with or upto 72 hours after cefamandole, cefaperazone,moxalactum, or cefotetan may produce acute alcohol intolerance(disulfram-like reaction). These four antibiotics possess a methyltetrazolethiol side chain that may inhibit aldehyde dehydrogenase .

The reaction begins within 30 minutes after alcohol ingestion and may subside 30 minutes to several hours afterwards, the reaction may occur up to 3 days after the last dose of the antibiotic

Anticoagulants incr Hypoprothrombinemic effects of anticoagulants may be increased by cephalosporins with the methyltetrazolethiol side chain (cefamandole, cefoperazone, cefotetan, moxalactum). Bleeding complications may occur.

The concurrent use of heparin may also theoritically increase the risk of bleeding. 

Urinary tract infection

Refer Cephalosporins

Refer Cephalosporins

Indication:

Urinary tract infection

Dosage:

Adults- usual dose is 1 or 2g IV or IM every 12 hours for 5 to 10 days

Refer Cephalosporins

Refer Cephalosporins

Refer Cephalosporins

Refer Cephalosporins