Enoxacin ( * ) - @ Fluoroquinolones
Drug Name:
Enoxacin ( * ) - @ Fluoroquinolones
List Of Brands:
Indication Type Description:
Pharmacology/ Pharmacokinetics
Drug Interaction:
Fluoroquinolones include the following :
Ciprofloxacin, Norfloxacin, Lomefloxacin, Ofloxacin, Pefloxacin, Enoxacin
Refer Ciprofloxacin
Interacting drugs- summary
+ Enoxacin-
Bismuth subsalicylate
enoxacin bioavailability is decreased when bismuth-
subsalicylate is given with or 60 minutes after enoxacin.
Avoid concurrent use
Enoxacin + Digitoxin
digoxin serum levels increased. Monitor digoxin levels.
Ciprofloxacin / Enoxacin / Norfloxacin + Caffeine
total body clearance is reduced, resulting in increased
pharmacologic effects. Ofloxacin and lomefloxacin do not appear
to affect caffeine. Enoxacin trough plasm levels were also higher.
Indication:
Sexually transmitted diseases, urinary tract infections.
Adverse Reaction:
Nausea, abdominal pain,
Diarrhoea, vomiting,
Dyspepsia, heartburn,
Headache, dizziness,
Drowsiness, paraethesia,
Hallucinations,rash.
Anorexia, bloody stools,
Gastritis, stomatitis.
Urticaria, hyperhidrosis,
Mycotic infection,
Erythema mutiforme
Contra-Indications:
Hypersens to fluroquinolones or the quinolone group of antibacterial agents(cinoxacin and
nalidixic acid)
Special precautions:
Monitor renal, hepatic, and hamatopoietic function, during prolonged therapy.
Cataracts and mutiple punctuate lenticular opacities.
Photosentive reactions at times severe when patients exposed to direct sunlight.
Superinfection. Use of antibiotics (prolonged use) may result in
bacterial or fungal infection.
Take precautions when superinfection occurs.
Dosages/ Overdosage Etc:
Approved by FDA on December 31,1991
ndications:
Sexually transmitted diseases, urinary tract infections.
Dosage:
Take atleast 1 hour before or 2 hours after a meal.
Urinary tract infection: (uncomplicated) 200mg 12 hourly for 7 days. Daily dose 400mg
Complicated- 400mg 12 hourly for 14 days. Daily dose 800mg
Sexually transmitted diseases- (uncomplicated) 400mg single dose 1 day. Daily dose 400mg.
Patient Information:
Refer fluoroquinolones
Pharmacology/ Pharmacokinetics:
Refer fluoroquinolones
Interaction with Food:
Refer fluoroquinolones
Pregnancy and lactation:
Refer fluoroquinolones