Xanthines- thiabendazole may compete with these agents for sites of metabolism and thus elevate serum levels of the xanthine to potentiate toxic levels. Monitor xanthine levels

Dizziness, weariness, Headache, numbness, hyperirritability, Convulsions collapse. Anorexia, nausea, diarrha, Epigastric distress, Jaundice, cholestasis.

Hypersensitivity

Special precutions:

Supportive therapy is indicated in anemic, dehydrated or malnoursihed patients.

Indication: Strongyloidiasis. thread worm infection

Dosage: Usual dosage schedule is 2 doses per day. Maximum daily dose is 3g after meals if possible

Pharmacokinetics:

Thiabendazole is rapidly absorbed and peak plasma concentations occur within 1 to 2 hours. Metabolised completely and occurs in the rine as conjugates. In 48 hrs about 5% of the administered dose is recovered in feces and 90% from urine.

May be administered without regard to ingestion of food or time of the day. May be taken with milk or fruit juices

Pregnancy: Use during pregnancy only when required

Lactation: Because of the potential hazard to the nursing infant, decide whether to discontinue nursing or discontinue the drug depending on the importance of the drug to the mother.