Mutually antagonostic with piperazine.

Roundworm infections

Anorexia, nausea, vomiting, abdominal cramps, diarrhoea, tanusmus, SGOT elevators, headache, dizziness, rash.

Pregnancy,children below 1 year.Concurrent use of piperazine Special precautions: Pregnancy, liver dysfunction.

Indications:

Roundworm infections

Dosage:

A single dose of 11mg/kg maximum dose is 1g.

Pharmacology:

Pyrental is a depolarizing neuromuscular blocking agent resulting in spastic paralysis of the worm. Pharmacokinetics: Pyrantel is poorly absorbed from the G I tract. Plasma levels of unchanged drug are low.

Not significant

Pregnancy: Do not use during pregnancy unless otherwise directed by the physician

Children: Safety and efficacy for use in children under 2 years have not been established