Effect potentiated by other anticholinergic drugs and tricyclic antidepressants

It significantly delays transit time of swallowed capsules in the oesophagus

Thus the absorption of concomitantly administered oral drugs is delayed.

Pre-anesthetic sedation and obstetric amnesia in conjunction with analgesics,calming delirium 

Refer Glycopyrrolate

Dryness of mouth,tachycardia,blurring of vision,drowsiness.

Eye drops: Prolonged use may lead to irritation,hyperaemia,oedema,conjuntivitis.Increase in intraocular pressure may occur especially in patients with closed angle glaucoma.

Occassionally psychotic reactions.

Transdermal delivery system:Bilateral mydrasis,contamination of finger and rubbing of eye may result in unilateral fixed dilation of pupil,glaucoma,contact dermititis,psychotic reactions Nausea and dizziness after removal.

Glaucoma,paralytic ileus,BHP.

Special Precautions:

Driving, elderly, hepatic/renal disease, pregnancy, lactation.

Indications:

Pre-anesthetic sedation and obstetric amnesia in conjunction with analgesics,calming delirium

Dosage:

Adults- 0.32 to 0.65mg SC or IM.give IV after dilution.

Children:

0.006mg/kg.Maximum dosage 0.3mg.

Refer - Glycopyrrolate

Observe caution while using pregnancy and lactation